World Journal of Surgical Oncology

Table 2 Univariate analysis for OS and EFS

From: The extremity localized classic osteosarcomas have better survival than the axial non-classics

Variable	OS		EFS
Variable	Median	P	Median	P
Gender
Male	43	0.735	14	0.478
Female	43		16
Age
≤ 40 years	46	0.101	22	0.116
> 40 years	18		6
Duration of symptoms
≤ 2 months	46	0.888	16	0.891
> 2 months	36		17
Tumor site
Extremity	51	<0.001	25	<0.001
Axial	14		5
Tumor size
≤ 8 cm	52	0.798	17	0.920
> 8 cm	36		16
Primary metastasis
No	51	0.001	25	0.042
Yes	14		10
Serum ALP
Normal	51	0.871	13	0.595
>ULN	52		22
Serum LDH
Normal	36	0.671	9	0.165
>ULN	NA^a		NA^a
Type of extremity surgery
Limb salvage	46	0.869	22	0.606
Amputation	NA^a		9.5

OS overall survival, EFS event-free survival, ALP alkaline phosphatase, LDH lactate dehydrogenase, ULN upper limit of normal
^aThe median OS and EFS are not available in >ULN LDH group, and median OS is not available in amputation surgery group because > 50% patients were free of events

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ISSN: 1477-7819

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