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Table 2 Univariate analysis for OS and EFS

From: The extremity localized classic osteosarcomas have better survival than the axial non-classics

Variable OS EFS
Median P Median P
Gender
 Male 43 0.735 14 0.478
 Female 43   16  
Age
 ≤ 40 years 46 0.101 22 0.116
 > 40 years 18   6  
Duration of symptoms
 ≤ 2 months 46 0.888 16 0.891
 > 2 months 36   17  
Tumor site
 Extremity 51 <0.001 25 <0.001
 Axial 14   5  
Tumor size
 ≤ 8 cm 52 0.798 17 0.920
 > 8 cm 36   16  
Primary metastasis
 No 51 0.001 25 0.042
 Yes 14   10  
Serum ALP
 Normal 51 0.871 13 0.595
 >ULN 52   22  
Serum LDH
 Normal 36 0.671 9 0.165
 >ULN NAa   NAa  
Type of extremity surgery
 Limb salvage 46 0.869 22 0.606
 Amputation NAa   9.5  
  1. OS overall survival, EFS event-free survival, ALP alkaline phosphatase, LDH lactate dehydrogenase, ULN upper limit of normal
  2. aThe median OS and EFS are not available in >ULN LDH group, and median OS is not available in amputation surgery group because > 50% patients were free of events