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Table 1 Baseline and treatment characteristics

From: The extremity localized classic osteosarcomas have better survival than the axial non-classics

Characteristic Classic Non-classic Total
Gender
 Male 43 17 60 (61.2%)
 Female 25 13 38 (38.8%)
Age
 0–10 13 1 14 (14.3%)
 11–20 40 9 49 (50.0%)
 21–30 10 1 11 (11.2%)
 31–40 5 5 10 (10.2%)
 41–50 4 4 (4.1%)
 51–60 6 6 (6.1%)
 > 60 4 4 (4.1%)
Duration of symptoms
 ≤ 2 months 45 16 61 (62.2%)
 > 2 months 23 14 37 (37.8%)
Tumor site
 Around knee 46 8 54 (55.1%)
  Distal femur 31 4 35 (35.7%)
  Proximal tibia 9 3 12 (12.2%)
  Proximal fibula 6 1 7 (7.1%)
 Proximal humerus 5 1 6 (6.1%)
 Other extremities 17 4 21 (21.4%)
 Axial 17 17 (17.3%)
Tumor size
 ≤ 8 cm 39 21 60 (61.2%)
 > 8 cm 29 9 38 (38.8%)
Primary metastasis
 No 68 19 87 (88.8%)
 Yes 11 11 (11.2%)
  Lung 9 9 (9.2%)
  Distal bones 1 1 (1.0%)
  Other sites 1 1 (1.0%)
Serum ALP    76 available
 Normal 20 7 27 (35.5%)
 >ULN 38 11 49 (64.5%)
Serum LDH    52 available
 Normal 25 12 37 (71.2%)
 >ULN 14 1 15 (28.8%)
Type of extremity surgery    81 available
 Limb salvage 28 10 38 (46.9%)
 Amputation 40 3 43 (53.1%)
  1. ALP alkaline phosphatase, LDH lactate dehydrogenase, ULN upper limit of normal