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Table 1 Baseline characteristics of the study patients

From: Risk factors of lateral lymph node metastasis in cN0 papillary thyroid carcinoma

   

With LLN metastasis

 
  

Total

Yes

No

P

Subjects, n

 

783

371

412

Gender

Male

207 (26.4)

115 (31.0)

92 (22.3)

0.006

 

Female

576 (73.6)

256 (69.0)

320 (77.7)

 

Age at diagnosis, years

 

42.4 ± 13.1

41.0 ± 13.7

43.8 ± 12.3

0.005

Age group, years

≤ 45

473 (60.0)

242 (65.2)

231 (56.1)

0.009

 

> 45

310 (40.0)

129 (34.8)

181 (43.9)

 

Tumor size, mm

 

17.2 ± 11.1

20.8 ± 12.2

14.0 ± 9.0

0.001

Tumor size group

≤ 10

306 (39.1)

94 (25.3)

212 (51.5)

0.001

 

10–20

315 (40.0)

161 (43.4)

154 (37.4)

 
 

> 20

162 (20.9)

116 (31.3)

46 (11.1)

 

Tumor location

Upper lobe

173 (22.1)

105 (28.3)

68 (16.5)

0.001a

 

Middle lobe

345 (44.1)

155 (41.8)

190 (46.1)

 
 

Lower lobe

217 (27.7)

75 (20.2)

142 (34.4)

 
 

Isthmus

19 (2.4)

11 (3.0)

8 (2.0)

 
 

Whole

29 (3.7)

25 (6.7)

4 (1.0)

 

ETE

Yes

157 (20.1)

96 (25.9)

61 (14.8)

0.001

 

No

626 (79.9)

275 (74.1)

351 (85.2)

 

Multifocality

Yes

94 (12.0)

54 (14.6)

40 (9.7)

0.037

 

No

689 (88.0)

317 (85.4)

372 (90.3)

 

Bilaterality

Yes

131 (16.7)

75 (20.2)

56 (13.6)

0.013

 

No

652 (83.3)

296 (79.8)

356 (86.4)

 

Hashimoto’s thyroiditis

Yes

92 (11.7)

46 (12.4)

46 (11.2)

0.592

 

No

691 (88.3)

325 (87.6)

366 (88.8)

 

CLN metastases

< 2

383 (48.9)

96 (25.9)

287 (69.7)

0.001

 

≥ 2

400 (51.1)

275 (74.1)

125 (30.3)

 
  1. Reported as n (%), unless noted otherwise. P values represent the statistically difference between the groups with and without LLN metastasis, unless noted otherwise
  2. aThe P value means the difference among the upper lobe, middle lobe, lower lobe, isthmus, and hole thyroid lobe