Fig. 2

SGEF expression is correlated with TNM stage and poor prognosis. a Representative images of SGEF staining in LAC specimen at different TNM stages. Magnification in the upper panel: × 40 (scale bar = 200 μm); magnification in the right panel: × 200 (scale bar = 20 μm). b IHC scores of SGEF expression in tumor of all stages. The expression of SGEF in TNM III stage was significantly higher than that in early TNMΙ and TNMΠ stages. c Kaplan–Meier analyses of 92 CRC patients showing that high-SGEF patients (n = 54) have shorter overall survival as compared with low-SGEF patients (n = 38). d Patients with highly expressed SGEF has a relatively higher risk of mortality (P < 0.001) from GEO databases