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Table 2 The clinical characteristics of patients based on whether pre-hepatectomy chemotherapy was performed or not

From: Clinical relevance of oncologic prognostic factors in the decision-making of pre-hepatectomy chemotherapy for colorectal cancer hepatic metastasis: the priority of hepatectomy

 

Oncologic scores ≥ 2

Oncologic scores < 2

Characteristics

Pre-hepatectomy chemotherapy

p value

Pre-hepatectomy chemotherapy

p value

Yes

N = 104 (%)

No

N = 162 (%)

Yes

N = 79 (%)

No

N = 131 (%)

Age (years), median (range)

58 (29–86)

61 (29–88)

0.034

59 (29–84)

62 (34–88)

0.017

Gender

  

0.201

  

0.601

 Male

64 (61.5)

112 (69.1)

 

54 (68.4)

94 (71.8)

 

 Female

40 (38.5)

50 (30.9)

 

25 (31.6)

37 (28.2)

 

Primary tumor location

  

0.337

  

0.336

 Right colon

14 (13.5)

29 (17.9)

 

11 (13.9)

25 (19.1)

 

 Left colon

90 (86.5)

133 (82.1)

 

68 (86.1)

106 (80.9)

 

Type of initial hepatic metastases

  

0.167

  

0.353

 Synchronous

84 (80.8)

141 (87.0)

 

20 (25.3)

26 (19.8)

 

 Metachronous

20 (19.2)

21 (13.0)

 

59 (74.7)

105 (80.2)

 

Serum CEA (ng/mL), median (range)

11.1 (0.5–16,259)

13.4 (0.5–2954.0)

0.190

7.0 (0.6–589.4)

9.4 (0.9–170.5)

0.849

Maximum tumor (cm), median (range)

3.5 (0.6–14.5)

3.3 (0.4–12.9)

0.316

2.5 (0.8–10.0)

2.5 (0.3–9.4)

0.813

Tumor number, median (range)

3.0 (1.0–17.0)

1.5 (1.0–11.0)

0.002

2.0 (1.0–7.0)

1.0 (1.0–4.0)

0.024

Primary lymph node

  

0.959

  

0.387

 Positive

89 (85.6)

139 (85.8)

 

38 (48.1)

55 (42.0)

 

 Negative

15 (14.4)

23 (14.2)

 

41 (51.9)

76 (58.0)