Table 4 The most enriched 10 Gene Ontology (GO) term in biological process (BP) analysis, cellular component (CC), and molecular functions (MF)
From: Clinical value of miR-198-5p in lung squamous cell carcinoma assessed using microarray and RT-qPCR
Category | Term | Count | P value |
|---|---|---|---|
GOTERM_BP_DIRECT | GO:0008544~epidermis development | 10 | 4.84E−04 |
GOTERM_BP_DIRECT | GO:0043524~negative regulation of neuron apoptotic process | 12 | 9.35E−04 |
GOTERM_BP_DIRECT | GO:0008284~positive regulation of cell proliferation | 26 | 9.70E−04 |
GOTERM_BP_DIRECT | GO:0060070~canonical Wnt signaling pathway | 9 | 0.001824 |
GOTERM_BP_DIRECT | GO:0007399~nervous system development | 18 | 0.002211 |
GOTERM_BP_DIRECT | GO:0071277~cellular response to calcium ion | 7 | 0.002457 |
GOTERM_BP_DIRECT | GO:0007269~neurotransmitter secretion | 7 | 0.002457 |
GOTERM_BP_DIRECT | GO:0090103~cochlea morphogenesis | 5 | 0.002641 |
GOTERM_BP_DIRECT | GO:0014075~response to amine | 4 | 0.002773 |
GOTERM_BP_DIRECT | GO:0006366~transcription from RNA polymerase II promoter | 26 | 0.003531 |
GOTERM_CC_DIRECT | GO:0030054~cell junction | 29 | 7.60E−05 |
GOTERM_CC_DIRECT | GO:0005667~transcription factor complex | 15 | 9.32E−04 |
GOTERM_CC_DIRECT | GO:0008021~synaptic vesicle | 10 | 9.61E−04 |
GOTERM_CC_DIRECT | GO:0009986~cell surface | 29 | 0.001109 |
GOTERM_CC_DIRECT | GO:0045202~synapse | 13 | 0.004398 |
GOTERM_CC_DIRECT | GO:0005876~spindle microtubule | 6 | 0.006912 |
GOTERM_CC_DIRECT | GO:0042734~presynaptic membrane | 7 | 0.007013 |
GOTERM_CC_DIRECT | GO:0043195~terminal bouton | 7 | 0.007013 |
GOTERM_CC_DIRECT | GO:0098793~presynapse | 7 | 0.008171 |
GOTERM_CC_DIRECT | GO:0005887~integral component of plasma membrane | 55 | 0.008929 |
GOTERM_MF_DIRECT | GO:0046983~protein dimerization activity | 15 | 8.03E−05 |
GOTERM_MF_DIRECT | GO:0005509~calcium ion binding | 36 | 9.88E−04 |
GOTERM_MF_DIRECT | GO:0016810~hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 4 | 0.00922 |
GOTERM_MF_DIRECT | GO:0005109~frizzled binding | 5 | 0.017408 |
GOTERM_MF_DIRECT | GO:0001105~RNA polymerase II transcription coactivator activity | 5 | 0.019099 |
GOTERM_MF_DIRECT | GO:0043565~sequence-specific DNA binding | 24 | 0.019304 |
GOTERM_MF_DIRECT | GO:0008080~N-acetyltransferase activity | 4 | 0.022413 |
GOTERM_MF_DIRECT | GO:0003682~chromatin binding | 19 | 0.026956 |
GOTERM_MF_DIRECT | GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 13 | 0.033582 |
GOTERM_MF_DIRECT | GO:0005262~calcium channel activity | 6 | 0.045673 |