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Table 4 Univariate analysis of factors for residual disease at reTURBT

From: Clinical rationale and safety of restaging transurethral resection in indication-stratified patients with high-risk non-muscle-invasive bladder cancer

Variable

Residual disease (%)

OR (95% CI)

p

Age

  

1.0 (1.0–1.1)

NS

Grade

LG

29%

1

 
 

HG

49%

2.4 (1.2–5.0)

0.018

Stage

Ta

57%

1

 
 

Tx(x)

17%

0.2 (0.01–2.1)

NS

 

Tx(a)

25%

0.3 (0.03–1.8)

NS

 

Tx(1)

41%

0.5 (0.1–2.6)

NS

 

T1

42%

0.6 (0.1–2.7)

NS

Tumor size

< 30 mm

33%

1

 
 

≥ 30 mm

43%

1.5 (0.7–3.4)

NS

Number of tumors

Single

39%

1

 
 

2–7

36%

0.9 (0.4–2.0)

NS

 

≥ 8

44%

1.3 (0.4–4)

NS

Disease history

Primary

43%

1

 
 

Recurrent

37%

0.8 (0.4–1.6)

NS

Indications

Single*

35%

1

 
 

Double**

42%

1.3 (0.6–3.0)

NS

 

Triple***

50%

1.9 (0.7–5.2)

NS

  1. Six Tx(x) cases were considered as missing data in double/triple vs. single indication analysis
  2. reTURT restaging transurethral resection of bladder tumor; CI confidence interval; NS not significant; OR odds ratio; HG high-grade; LG low-grade; Tx(x) both detrusor muscle and subepithelial connective tissue lacking in the specimen; Tx(a) no intraepithelial invasion within available material, but detrusor muscle lacking in the specimen; Tx (1) intraepithelial invasion within available material and detrusor muscle lacking in the specimen
  3. *Single indication—Tx(a)LG, T1LG, TaHG
  4. **Double indication—Tx(1)LG, Tx(a)HG, T1HG
  5. ***Triple indication—Tx(1)HG