Skip to main content

Table 3 Association of the 2-year overall survival and disease-free survival with different clinicopathological variables and biomarkers

From: Effect of neoadjuvant chemotherapy and its correlation with HPV status, EGFR, Her-2-neu, and GADD45 expression in oral squamous cell carcinoma

  2-year overall survival (OS) (%) p value 2-year disease-free survival (DSF) (%) p value
Gender
 Male 89.5 0.00* 73.7 0.00*
 Female 0 0
T stage
 T2 100 0.541 33.3 0.18
 T3 100 50
 T4 75 75
N stage
 N0 100 0.738 100 0.422
 N1 75 50
 N2 81.8 72.7
Skin involvement
 Present 100 0.242 100 0.095
 Absent 75 56.2
Bone involvement
 Present 90 0.282 90 0.023*
 Absent 72.7 45.5
GADD45
 0 0 0.005* 0 0.012*
 1 100 100
 2 83.3 58.3
 3 100 100
HPV status
 Positive 100 0.234 100 0.077**
 Negative 75 56.2
EGFR grading
 1 83.3 0.566 83.3 0.518
 2 60 40
 3 90 70
Her-2-neu
 Positive 100 0.392 66.7 0.933
 Negative 77.8 66.7
Pathological lymph node involvement
 Present 81.8 0.899 63.7 0.47
 Absent 80 70
Vascular invasion
 Present 71.4 0.273 66.7 0.86
 Absent 88.9 71.4
Perineural invasion
 Present 57.1 0.05* 57.1 0.36
 Absent 100 77.8
Lymphatic invasion
 Present 71.4 0.273 66.7 0.86
 Absent 88.9 71.4
  1. *statistically significant; **approaching statistical significance