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Table 3 Association of the 2-year overall survival and disease-free survival with different clinicopathological variables and biomarkers

From: Effect of neoadjuvant chemotherapy and its correlation with HPV status, EGFR, Her-2-neu, and GADD45 expression in oral squamous cell carcinoma

 

2-year overall survival (OS) (%)

p value

2-year disease-free survival (DSF) (%)

p value

Gender

 Male

89.5

0.00*

73.7

0.00*

 Female

0

0

T stage

 T2

100

0.541

33.3

0.18

 T3

100

50

 T4

75

75

N stage

 N0

100

0.738

100

0.422

 N1

75

50

 N2

81.8

72.7

Skin involvement

 Present

100

0.242

100

0.095

 Absent

75

56.2

Bone involvement

 Present

90

0.282

90

0.023*

 Absent

72.7

45.5

GADD45

 0

0

0.005*

0

0.012*

 1

100

100

 2

83.3

58.3

 3

100

100

HPV status

 Positive

100

0.234

100

0.077**

 Negative

75

56.2

EGFR grading

 1

83.3

0.566

83.3

0.518

 2

60

40

 3

90

70

Her-2-neu

 Positive

100

0.392

66.7

0.933

 Negative

77.8

66.7

Pathological lymph node involvement

 Present

81.8

0.899

63.7

0.47

 Absent

80

70

Vascular invasion

 Present

71.4

0.273

66.7

0.86

 Absent

88.9

71.4

Perineural invasion

 Present

57.1

0.05*

57.1

0.36

 Absent

100

77.8

Lymphatic invasion

 Present

71.4

0.273

66.7

0.86

 Absent

88.9

71.4

  1. *statistically significant; **approaching statistical significance