Table 2 Study population and clinicopathological characteristics according to the development of PHLF
Variables | PHLF (−) (n = 285) | PHLF (+) (n = 35) | P |
|---|---|---|---|
Age, years | 51.2 ± 10.5 | 53.3 ± 11.1 | 0.255 |
BMI, Kg/m2 | 22.6 ± 3.1 | 22.3 ± 3.4 | 0.589 |
PLT, × 109/l | 161.7 ± 80.2 | 115.6 ± 63.0 | 0.001 |
ALT, U/l | 41.9 ± 31.0 | 50.3 ± 44.2 | 0.153 |
AST, U/l | 44.2 ± 22.8 | 55.5 ± 31.8 | 0.050 |
ALB, g/l | 38.3 ± 4.2 | 37.2 ± 4.8 | 0.129 |
PT, s | 13.1 ± 1.2 | 13.1 ± 1.3 | 0.946 |
INR | 1.1 ± 0.1 | 1.0 ± 0.1 | 0.513 |
CREA, umol/l | 74.6 ± 11.9 | 69.0 ± 12.9 | 0.010 |
TBIL, umol/l | 14.6 ± 6.6 | 19.0 ± 10.7 | 0.020 |
Tumor size, cm | 6.1 ± 3.2 | 7.3 ± 3.4 | 0.030 |
Operation time, min | 187.5 ± 59.3 | 198.5 ± 63.8 | 0.307 |
ICG R15, % | 7.1 ± 4.2 | 9.7 ± 5.4 | 0.010 |
ST, mm | 36.5 ± 8.4 | 45.5 ± 10.9 | < 0.001 |
Blood loss, ml | 526.6 ± 502.5 | 1135.7 ± 1475.1 | 0.021 |
PVD, mm | 11.0 ± 2.0 | 11.1 ± 1.4 | 0.800 |
PVT | 0.223 | ||
Positive | 47 (16.5%) | 3 (8.6%) | |
Negative | 238 (83.5%) | 32 (91.4%) | |
EV | 0.281 | ||
Positive | 38 (13.3%) | 2 (5.7%) | |
Negative | 247 (86.7%) | 33 (94.3%) | |
CSPH | < 0.001 | ||
Positive | 69 (24.2%) | 19 (54.3%) | |
Negative | 216 (75.8%) | 16 (45.7%) | |
Cirrhosis | 0.108 | ||
Positive | 199 (69.8%) | 29 (82.9%) | |
Negative | 86 (30.2%) | 6 (17.1%) | |
Liver resection | 0.036 | ||
Minor | 237 (83.2%) | 24 (68.6%) | |
Major | 48 (16.8%) | 11 (31.4%) | |
Child-Pugh grade | 0.128 | ||
A | 260 (91.2%) | 29 (82.9%) | |
B | 25 (8.8%) | 6 (17.1%) | |
MELD | 0.193 | ||
< 7.5 | 250 (87.7%) | 28 (80.0%) | |
≥ 7.5 | 35 (12.3%) | 7 (20.0%) |