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Table 1 Characteristics of patients with normal or thickened spleen

From: Predictive power of splenic thickness for post-hepatectomy liver failure in HBV-associated hepatocellular carcinoma patients

Variables

No. of patients (n = 320)

Normal (n = 223)

Thickening (n = 97)

P

Age, years

51.4 ± 10.6

51.3 ± 10.9

51.7 ± 9.7

0.754

Gender

   

0.531

 Male

285 (89.1%)

197 (88.3%)

88 (90.7%)

 

 Female

35 (10.9%)

26 (11.7%)

9 (9.3%)

 

BMI, Kg/m2

22.6 ± 3.2

22.5 ± 3.1

22.8 ± 3.3

0.436

PLT, × 109/l

156.7 ± 79.7

177.9 ± 76.1

107.7 ± 65.3

< 0.001

ALT, U/l

42.8 ± 32.8

41.2 ± 26.7

46.5 ± 43.6

0.267

AST, U/l

45.5 ± 24.2

44.9 ± 21.8

46.6 ± 28.9

0.575

ALB, g/l

38.2 ± 4.2

38.3 ± 4.0

38.1 ± 4.8

0.596

PT, s

13.1 ± 1.2

12.9 ± 1.2

13.5 ± 1.3

< 0.001

INR

1.1 ± 0.1

1.0 ± 0.1

1.1 ± 0.1

< 0.001

CREA, umol/l

73.9 ± 12.1

74.1 ± 12.1

73.8 ± 12.1

0.744

TBIL, umol/l

15.1 ± 7.2

13.9 ± 6.3

17.7 ± 8.5

< 0.001

Tumor size, cm

6.2 ± 3.2

6.4 ± 3.2

5.8 ± 3.2

0.131

Operation time, min

188.7 ± 59.8

187.8 ± 58.9

190.8 ± 62.1

0.684

ICG R15, %

7.4 ± 4.4

6.7 ± 3.3

9.2 ± 6.0

< 0.001

ST, mm

37.5 ± 9.2

32.4 ± 3.0

49.3 ± 7.7

< 0.001

Blood loss, ml

593.2 ± 702.1

563.7 ± 721.5

661.0 ± 653.9

0.255

PVD, mm

11.0 ± 1.9

10.5 ± 1.5

12.3 ± 2.3

< 0.001

PVT

   

0.958

 Positive

50 (15.6%)

35 (15.7%)

15 (15.5%)

 

 Negative

270 (84.4%)

188 (84.3%)

82 (84.5%)

 

EV

   

< 0.001

 Positive

40 (12.5%)

12 (5.4%)

28 (28.9%)

 

 Negative

280 (87.5%)

211 (94.6%)

69 (71.1%)

 

CSPH

   

< 0.001

 Positive

88 (27.5%)

23 (10.3%)

65 (67.0%)

 

 Negative

232 (72.5%)

200 (89.7%)

32 (33.0%)

 

Cirrhosis

   

< 0.001

 Positive

228 (71.2%)

140 (62.8%)

88 (90.7%)

 

 Negative

92 (28.8%)

83 (37.2%)

9 (9.3%)

 

Liver resection

   

0.126

 Minor

261 (81.6%)

177 (79.4%)

84 (86.6%)

 

 Major

59 (18.4%)

46 (20.6%)

13 (13.4%)

 

Complication

   

< 0.001

 None

252 (78.8%)

203 (91.0%)

49 (50.5%)

 

 Minor

43 (13.4%)

11 (4.9%)

32 (33.0%)

 

 Major

25 (7.8%)

9 (4.0%)

16 (16.5%)

 

Child-Pugh grade

   

0.021

 A

289 (90.3%)

207 (92.8%)

82 (84.5%)

 

 B

31 (9.7%)

16 (7.2%)

15 (15.5%)

 

MELD

    

 < 7.5

278 (86.9%)

203 (91.0%)

75 (77.3.0%)

0.001

 ≥ 7.5

42 (13.1%)

20 (9.0%)

22 (22.7%)

 
  1. Abbreviation: BMI body mass index, PLT platelet counts, ALT alanine transaminase, AST aspartate aminotransferase, ALB albumin, PT prothrombin time, INR international normalized ratio, CREA creatinine, TBIL total bilirubin, ST splenic thickness, PVD portal vein diameter, PVT portal vein thrombus, EV esophageal varices, CSPH clinically significant portal hypertension, ICG R15 indocyanine green retention rate 15 min, MELD the model for end-stage liver disease
  2. Data are expressed as means ± SD or n (%)