Table 5 Acute and late toxicity due to CRT
ACUTE | LATE | |||
|---|---|---|---|---|
Preop. CRT (n = 177) | Postop. CRT (n = 159) | Preop. CRT (n = 177) | Postop. CRT (n = 159) | |
Grade II | 46 | 33 | N/A | N/A |
Grade III | 19 | 29 | 12 | 17 |
Grade IV | 2 | 1 | 1 | 4 |
Grade V | 3 | 1 | – | – |
Total | 70 | 64 | 13 | 21 |
Grade III gastrointestinal system toxicity | ||||
Diarrhea (IV replacement) | 10 | 24 | – | – |
Pad usage | 2 | 2 | – | – |
Obstruction (need surgery) | – | – | 2 | 5 |
Anast. stenosis | – | – | 5 | 9 |
Grade III genitourinary system toxicity | ||||
Pollakuria (hourly) | 1 | – | – | – |
Disuria, pelvic pain | 1 | – | – | – |
Obst. üropathy-hydronephrosis | – | – | 5 | 3 |
Grade III hematologic toxicity | ||||
Platelets 25 < 50 | 1 | 1 | – | – |
WBC 1.0 < 2.0 | 1 | 2 | – | – |
Neutrophils 0.5 < 1.0 | 3 | – | – | – |
Grade IV gastrointestinal system toxicity | ||||
Obstr. | 1 | – | – | – |
Perforation | – | – | – | 1 |
Colovesical fistula | – | – | – | 1 |
Rectovesical—vaginal fistula | – | – | – | 2 |
Enterocutaneous fistula | – | – | 1 | – |
Grade IV hematologic toxicity | ||||
WBC < 10 | 1 | 1 | – | – |