Table 3 Histopathological results of 336 eligible patients
Preop. CRT (n = 177) | Postop. CRT (n = 159) | p value | |
|---|---|---|---|
R classification—n (%) | 0.172 | ||
R0 | 163 (92.1) | 139 (87.4) | |
*R1 | 14 (7.9) | 20 (12.6) | |
pT category—n (%) | p < 0.001 | ||
T0 | 24 (13.5) | – | |
T1 | 10 (5.5) | 2 (1.3) | |
T2 | 36 (20.0) | 6 (3.8) | |
T3 | 92 (52.0) | 133 (83.6) | |
T4a | 8 (4.5) | 16 (9.6) | |
T4b | 8 (4.5) | 2 (1.3) | |
pN category—n (%) | p < 0.001 | ||
N0 | 120 (67.8) | 80 (50.3) | |
N1a | 25 (14.1) | 25 (15.7) | |
N1b | 15 (8.5) | 26 (16.4) | |
N1c | 3 (1.7) | 2 (1.3) | |
N2a | 11 (6.2) | 10 (6.3) | |
N2b | 3 (1.7) | 16 (10.1) | |
Stage—n (%) | p < 0.001 | ||
**Grade 0/PCR | 23 (13.0) | – | |
Grade 1 | 36 (20.0) | – | |
Grade 2a | 50 (28.2) | 74 (46.5) | |
2b | 7 (4.1) | 4 (2.5) | |
2c | 4 (2.3) | 2 (1.3) | |
Grade 3a | 11 (6.3) | 8 (5.0) | |
3b | 39 (22.0) | 53 (33.3) | |
3c | 7 (4.1) | 18 (11.3) | |
Differentiation—n (%) | 0.091 | ||
Well differentiation | 15 (8.4) | 16 (10.1) | |
Moderate differentiation | 146 (82.5) | 114 (71.7) | |
Poor differentiation—signed ring cell | 7 (4.0) | 14 (8.8) | |
Mucineous | 9 (5.1) | 15 (9.4) | |
+ PNI—n (%) | 0.008 | ||
Present | 10 (5.5) | 23 (14.5) | p < 0.001 |
++ LVI—n (%) | |||
Present | 3 (1.7) | 20 (12.6) |