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Table 3 Comparison of cases with false-negative BRAF results and other cases

From: False-negative BRAF V600E mutation results on fine-needle aspiration cytology of papillary thyroid carcinoma

Variable

Group 1 (n = 36)

Group 2 (n = 185)

P value

(FN group)

(TP + FP + TN group)

 

Gender (F/M)

33/3 (91.7%)

146/39 (78.9%)

0.121

Age

51.7 ± 9.5

45.6 ± 12.8

0.002

Tumor size

0.78 ± 0.72

0.93 ± 0.70

0.241

Extrathyroidal extension

17 (47.2%)

56 (30.3%)

0.074

Lymph node metastasis

20 (55.6%)

92 (49.7%)

0.647

Bethesda system

  

< 0.001

 Nondiagnostic

10 (27.8%)

6 (3.2%)

 

 Benign

0

0

 

 AUS

4 (11.1%)

7 (3.8%)

 

 (Suspicious) FN

0

0

 

 Suspicious

11 (30.6%)

28 (15.1%)

 

 Malignant

11 (30.6%)

144 (77.8%)

 

Subtype of PTC

  

0.036

 Conventional

30 (83.3%)

131 (70.8%)

 

 Follicular variant

4 (11.1%)

43 (23.2%)

 

 Clear cell variant

0

3 (1.6%)

 

 Oncocytic variant

0

7 (3.8%)

 

 Tall cell variant

2 (5.6%)

1 (0.5%)

 
  1. FN false-negative, TP true-positive, FP false-positive, TN true-negative