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Table 2 Comparison of BRAF testing results on FNAC with those on FFPE tissue

From: False-negative BRAF V600E mutation results on fine-needle aspiration cytology of papillary thyroid carcinoma

 

On FFPE tissue

BRAF status

 

Positive

Negative

On FNAC

Positive

149 TP

1 FP

 

Negative

36 FN

35 TN

  1. Sensitivity = 149/185 = 80.5%
  2. Specificity = 35/36 = 97.2%
  3. Positive predictive value = 149/150 = 99.3%
  4. Negative predictive value = 35/71 = 49.3%
  5. TP true-positive, FP false-positive, FN false-negative, TN true-negative