Impact of surgical resection extension on outcome for primary well-differentiated thyroid cancer—a retrospective analysis

Table 2 Surgery-related morbidity

Parameter	Total	One-stage surgery		Two-stage surgery	p value
Parameter		Thyroidectomy with no LND	Thyroidectomy with LND	Completion surgery
n (%)	n = 87	n = 30 (34.5%)	n = 26 (29.9%)	n = 31 (35.6%)
Bleeding requiring surgery	2 (2%)	1 (3%)	0	1 (3%)	1.000
Transient postoperative hypocalcemia^a	48 (55%)	10 (33%)	18 (69%)	20 (65%)	0.013
Persistent hypocalcemia (> 6 months)^b	8 (9%)	3 (10%)	3 (12%)	2 (7%)	0.416
Surgery-related transient RLNP	6/84 (7%)	1 (3%)	0	5 (16%)	0.058
Surgery-related permanent RLNP	2/84 (2%)	0	0	2 (7%)^c	0.329

RLNP recurrent laryngeal nerve palsy
^aBiochemical hypocalcemia measured within the first 48 h
^bBiochemical hypocalcemia and/or substitution of calcium and/or vitamin D
^cOne patient suffering from persistent hypocalcemia and surgery-related permanent RLNP

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