Table 2 Combined overall and subgroup results
From: The association between dietary protein intake and colorectal cancer risk: a meta-analysis
Subgroups | No. cases | No. studies | RR (95% CI) | I 2 (%) | P heterogeneity |
|---|---|---|---|---|---|
All studies | 8187 | 21 | 1.006(0.857–1.179) | 53.4 | 0.002 |
Disease type | |||||
Colon | 3446 | 9 | 1.135(0.871–1.480) | 55.4 | 0.022 |
Rectum | 282 | 2 | 0.773(0.538–1.111) | 0.0 | 0.363 |
Study design | |||||
Cohort | 680 | 4 | 0.939(0.730–1.209) | 0.0 | 0.980 |
Case-control | 7507 | 17 | 1.030(0.846–1.254) | 62.6 | 0.000 |
Sex | |||||
Both | 4394 | 10 | 0.913(0.737–1.132) | 53.3 | 0.023 |
Men | 2204 | 5 | 1.306(0.932–1.829) | 54.6 | 0.066 |
Women | 1589 | 6 | 0.931(0.710–1.220) | 20.5 | 0.279 |
Protein | |||||
Total | 6858 | 16 | 1.049(0.856–1.285) | 60.6 | 0.001 |
Animal | 1359 | 5 | 1.041(0.866–1.252) | 0.0 | 0.624 |
Vegetable | 1144 | 4 | 0.851(0.602–1.203) | 49.9 | 0.112 |
Geographic locations | |||||
America | 5711 | 11 | 1.072(0.838–1.372) | 56.4 | 0.011 |
Asia | 1790 | 7 | 0.962(0.694–1.333) | 69.0 | 0.004 |
Europe | 686 | 3 | 0.972(0.738–1.280) | 0.0 | 0.785 |