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Table 2 Combined overall and subgroup results

From: The association between dietary protein intake and colorectal cancer risk: a meta-analysis

Subgroups No. cases No. studies RR (95% CI) I 2 (%) P heterogeneity
All studies 8187 21 1.006(0.857–1.179) 53.4 0.002
Disease type
 Colon 3446 9 1.135(0.871–1.480) 55.4 0.022
 Rectum 282 2 0.773(0.538–1.111) 0.0 0.363
Study design
 Cohort 680 4 0.939(0.730–1.209) 0.0 0.980
 Case-control 7507 17 1.030(0.846–1.254) 62.6 0.000
Sex
 Both 4394 10 0.913(0.737–1.132) 53.3 0.023
 Men 2204 5 1.306(0.932–1.829) 54.6 0.066
 Women 1589 6 0.931(0.710–1.220) 20.5 0.279
Protein
 Total 6858 16 1.049(0.856–1.285) 60.6 0.001
 Animal 1359 5 1.041(0.866–1.252) 0.0 0.624
 Vegetable 1144 4 0.851(0.602–1.203) 49.9 0.112
Geographic locations
 America 5711 11 1.072(0.838–1.372) 56.4 0.011
 Asia 1790 7 0.962(0.694–1.333) 69.0 0.004
 Europe 686 3 0.972(0.738–1.280) 0.0 0.785