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Table 5 Summary of Median Overall Survivals in the various studies included in the current review

From: Neoadjuvant treatment of pancreatic adenocarcinoma: a systematic review and meta-analysis of 5520 patients

  

Overall survival (months)

  

All patients

Resected

Not resected

Resectable

Median (range)

18.2 (13–28)

30.0 (24.5–46)

10 (9–11)

 

n

9

8

5

Borderline resectable

Median (range)

19.2 (9.1–45)

27.4 (19.3–41.2)

12.9 (9–15.5)

 

n

11

8

7

Locally advanced

Median (range)

13.6 (7.3–32.5)

18.7 (14.4–24.9)

12.6 (8–19.7)

 

n

28

8

7

BR + LA

Median (range)

14.7 (10.6–47.2)

26 (13–47.4)

12.4 (8.8–17)

 

n

16

11

9

All patients

Median (range)

15.3 (7.3–47.2)

24.4 (11.7–47.4)

11.5 (5.7–19.7)

 

n

63

39

32

Progression-free survival (months)

  

All patients

Resected

Not resected

Resectable

Median (range)

8.4 (6.2–10.4)

14.9 (8.4–23)

11*

 

n

2

4

1

Borderline resectable

Median (range)

9 (2.4–21.1)

15.4 (4.7–23.2)

2.1*

 

n

6

6

1

Locally advanced

Median (range)

9.3 (4–17.6)

12.9 (9.6–22.5)

5.7 (4–8)

 

n

20

6

3

BR + LA

Median (range)

9.9 (6.5–27.4)

12.5 (9–19.7)

7.5 (7.1–7.6)

 

n

9

4

2

All patients

Median (range)

9.3 (2.4–27.4)

12.9 (4.7–23.2)

5.8 (2.1–11)

 

n

31

20

7

  1. *Only one observation. n number of studies reporting the outcome. Values in parenthesis indicate ranges