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Table 4 Surgical exploration and resection rates after neoadjuvant therapy

From: Neoadjuvant treatment of pancreatic adenocarcinoma: a systematic review and meta-analysis of 5520 patients

Surgical treatment

Explored/N

Resected/N

R0/N

Resected/explored

R0/resected

Resectable

86%

76%

63%

92%

88%

[79–92%]

[68–84%]

[51–75%]

[85–97%]

[80–94%]

I 2 = 83.91%

I 2 = 86.02%

I 2 = 90.69%

I 2 = 83.37%

I 2 = 81.82%

(n = 18)

(n = 18)

(n = 14)

(n = 18)

(n = 14)

Borderline resectable

77%

69%

54%

91%

84%

[66–86%]

[59–78%]

[37–71%]

[84–96%]

[67–96%]

I 2 = 87.62%

I 2 = 88.98%

I 2 = 95.15%

I 2 = 70.68%

I 2 = 93.75%

(n = 15)

(n = 18)

(n = 16)

(n = 15)

(n = 16)

Locally advanced

32%

26%

23%

86%

82%

[23–42%]

[19–34%]

[15–33%]

[73–95%]

[69–93%]

I 2 = 91.44%

I 2 = 89.42%

I 2 = 91.18%

I 2 = 86.04%

I 2 = 82.75%

(n = 22)

(n = 24)

(n = 18)

(n = 19)

(n = 15)

BR + LA

65%

53%

39%

89%

85%

[49–79%]

[36–70%]

[27–52%]

[80–96%]

[79–90%]

I 2 = 95.67%

I 2 = 96.04%

I 2 = 92.74%

I 2 = 85.80%

I 2 = 35.55%

(n = 20)

(n = 22)

(n = 20)

(n = 19)

(n = 19)

All patients

64%

55%

45%

91%

85%

[57% -71%]

[48–62%]

[38–52%]

[87–94%]

[80–89%]

I 2 = 95.27%

I 2 = 95.34%

I 2 = 94.94%

I 2 = 84.53%

I 2 = 85.05%

(n = 84)

(n = 90)

(n = 74)

(n = 79)

(n = 70)

  1. Values in [] reflect the 95% confidence interval. I 2 is a quantitative indicator of heterogeneity among the studies, n refers to the number of studies reporting the outcomes