Fig. 2From: Intraoperative 5-aminolevulinic acid-induced photodynamic diagnosis of metastatic brain tumors with histopathological analysisRepresentative metastatic tumor with strong PpIX fluorescence (case 5). a Gadolinium-enhanced T1-weighted MRI showing a left frontal metastatic tumor in a rectal cancer patient. b The resected tumor was sectioned and observed under the fluorescence mode. The tumor was divided into fluorescing (F) and nonfluorescing (N) sections. c HE staining of the fluorescent section shows typical adenocarcinoma with tubular formation (×200 magnification). d HE staining of the nonfluorescing section shows the same histopathological findings as the fluorescent section. There are no necrotic changes (×200 magnification)Back to article page