Skip to main content
Fig. 1 | World Journal of Surgical Oncology

Fig. 1

From: Intraoperative 5-aminolevulinic acid-induced photodynamic diagnosis of metastatic brain tumors with histopathological analysis

Fig. 1

Representative metastatic tumor with absence of PpIX fluorescence (case 4). a Gadolinium-enhanced T1-weighted MRI revealing a right occipital metastatic tumor adjusting to the lateral ventricle in a breast cancer patient. b This picture shows a tumor removal cavity after the resection of the main tumor bulk which did not show any fluorescence of PpIX. Arrowheads indicate a residual tumor tissue. c The residual tumor (T) showed no fluorescence of PpIX as well as its main tumor bulk. In contrast, vague fluorescence was observed in some parts of the adjacent white matters (W) on the surface of the tumor-removal cavity. d Histopathology of the PpIX fluorescence-positive white matter (W) in c, stained with hematoxylin and eosin (HE). Clusters of cancer cells (arrowheads) were seen in the normal brain parenchyma. e Vague PpIX fluorescence was also seen in the exposed ventricular wall after the tumor removal. f: Infiltrating cancer cells were seen in the subventricular zone (arrowhead). HE ×200 magnification

Back to article page