Table 3 Plasma concentrations of IL-6, cortisol, LXA4, and RvD in patients with and without postoperative complications
From: Inflammation and pro-resolution inflammation after hepatobiliary surgery
Cytokine | Median preoperative [IQR] | Median POD-1 [IQR] | Median POD-3 [IQR] | Median POD-5 [IQR] |
|---|---|---|---|---|
IL-6, pg/mL | ||||
Complications, n = 9 | 34 [19.33–46.25] | 254 [82.25–593.3] | 98 [54.75–268.3] | 76 [50–284.8] |
No complications, n = 31 | 27 [0–115] | 206 [38–359] | 128 [44–286] | 59 [3–163] |
P value | 0.999 | 0.999 | 0.999 | 0.991 |
Cortisol, pg/mL | ||||
Complications, n = 9 | 28.1 [13.60–40.66] | 34.75 [31.19–87.6] | 27.72 [8.46–46.2] | 30.88 [16.4–48.3] |
No complications, n = 29 | 33.34 [16.8–54.37] | 40 [25.69–81.35] | 39.12 [17.96–51.78] | 40.36 [13.52–56.21] |
p value | 0.999 | 0.999 | 0.999 | 0.999 |
LXA4, pg/mL | ||||
Complications, n = 9 | 3.95 [1.57–19.52] | 3.2 [1.05–6.25] | 3.15 [1.12–8.63] | 2.87 [1.23–6.01] |
No complications, n = 31 | 7 [2.01–17.24] | 4.21 [1.48–8.99] | 4.93 [1.68–10.64] | 5.96 [2.27–13.63] |
p value | 0.999 | 0.968 | 0.999 | 0.534 |
RvD, pg/mL | ||||
Complications, n = 9 | 1.13 [0.56–1.85] | 0.43 [0.28–1.5] | 0.76 [0.28–1.03] | 1.02 [0.48–1.39] |
No complications, n = 27 | 0.89 [0.6–1.5] | 0.68 [0.47–1.03] | 0.98 [0.67–1.93] | 1.01 [0.69–2] |
p value | 0.999 | 0.435 | 0.501 | 0.999 |