E-cadherin expression phenotypes associated with molecular subtypes in invasive non-lobular breast cancer: evidence from a retrospective study and meta-analysis

Table 5 Pooled analysis of E-cad expression between molecular subtypes of breast cancer

Comparisons	No. of studies	Molecular subtypes	No. of patients	E-cad expression		χ ² (P value)
Comparisons	No. of studies	Molecular subtypes	No. of patients	Negative/low	Positive	χ ² (P value)
1	4^a [11, 24, 25]	Luminal A	523	97	426	137.90 (0.000)
		Luminal B	305	74	231
		HER2-enriched	208	57	151
		TNBC	325	180	145
2	7^a [11, 17, 24, 25, 27, 28]	Luminal A/B	2140	552	1588	86.34 (0.000)
		HER2-enriched	545	145	400
		TNBC	744	324	420
3	12^a [11, 12, 16, 17, 22,23,24,25,26,27,28]	Non-TNBC	5254	1909	3345	120.46 (0.000)
3	12^a [11, 12, 16, 17, 22,23,24,25,26,27,28]	TNBC	1273	676	597	120.46 (0.000)

ISSN: 1477-7819