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Table 5 Pooled analysis of E-cad expression between molecular subtypes of breast cancer

From: E-cadherin expression phenotypes associated with molecular subtypes in invasive non-lobular breast cancer: evidence from a retrospective study and meta-analysis

Comparisons No. of studies Molecular subtypes No. of patients E-cad expression χ 2 (P value)
Negative/low Positive
1 4a [11, 24, 25] Luminal A 523 97 426 137.90 (0.000)
Luminal B 305 74 231
HER2-enriched 208 57 151
TNBC 325 180 145
2 7a [11, 17, 24, 25, 27, 28] Luminal A/B 2140 552 1588 86.34 (0.000)
HER2-enriched 545 145 400
TNBC 744 324 420
3 12a [11, 12, 16, 17, 22,23,24,25,26,27,28] Non-TNBC 5254 1909 3345 120.46 (0.000)
TNBC 1273 676 597
  1. TNBC triple-negative breast cancer
  2. aIncluding our retrospective study