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Table 1 Clinical characteristics of the tertiary debulking surgery (TDS) group and non-TDS group

From: Current status of tertiary debulking surgery and prognosis after secondary debulking surgery for recurrent Müllerian epithelial cancer in Japan: a retrospective analysis of 164 patients (KCOG-G1402)

Characteristics TDS (n = 43) Non-TDS (n = 55) P value
Primary
 Age, median (range), years 56.9 (35–74) 54.2 (27–77)  
  <60 24 (55.8%) 35 (63.6%) 0.432
  60 19 (44.2%) 20 (36.4%)  
 Cancer
  Ovary 42 (97.7%) 51 (92.7%) 0.415
  Fallopian tube 0 (0%) 2 (3.6%)  
  Peritoneum 1 (2.3%) 2 (3.6%)  
 FIGO stage
 I, II 10 (23.3%) 13 (23.6%) 0.965
 III, IV 33 (76.7%) 42 (76.4%)  
 Histology
  Serous 22 (51.2%) 36 (65.5%) 0.333
  Endometrioid 6 (14.0%) 4 (7.3%)  
  Clear cell 10 (23.3%) 6 (10.9%)  
  Mucinous 2 (4.7%) 3 (5.5%)  
  Others 3 (7.0%) 6 (10.9%)  
 CA 125 (U/ml)
   < 100 10 (23.3%) 7 (12.7%) 0.086
  100 21 (48.8%) 38 (69.1%)  
  Missing 12 (27.9%) 10 (18.2%)  
 Residual disease at PDS, mm
  0 34 (79.1%) 33 (60.0%) 0.035
  0-10 8 (18.6%) 11 (20%)  
  10 1 (2.3%) 10 (18.2%)  
  Missing 0 (0%) 1 (1.8%)  
Recurrence at SDS
 Age, median (range), years 59.5 (40–76) 56.8 (32–79)  
  <60 20 (46.5%) 30 (54.5%) 0.430
  60 23 (53.5%) 25 (45.5%)  
 Platinum-free interval
  <6 months 4 (9.3%) 3 (5.5%) 0.09
  6–12 months 13 (30.2%) 9 (16.4%)  
  12 months 22 (51.2%) 42 (76.4%)  
  Missing 4 (9.3%) 1 (1.8%)  
 CA 125 (U/ml)
  <100 32 (74.4%) 37 (67.3%) 0.410
  100 8 (18.6%) 14 (25.5%)  
  Missing 3 (7.0%) 4 (7.3%)  
 Peritonitis carcinomatosa
  No 39 (90.7%) 48 (87.3%) 0.920
  Yes 3 (7.0%) 4 (7.3%)  
  Missing 1 (2.3%) 3 (5.5%)  
 Residual disease at SDS, mm
  0 38 (88.4%) 44 (80.0%) 0.092
  0–10 1 (2.3%) 8 (14.5%)  
  10 2 (4.7%) 1 (1.8%)  
  Missing 2 (4.7%) 2 (3.6%)  
Recurrence at TDS
 Age, median (range), years 61.5 (40–78) 58.6 (33–80)  
  <60 17 (39.5%) 28 (50.9%) 0.262
  60 26 (60.5%) 27 (49.1%)  
 CA 125 (U/ml)
  <100 31 (72.1%) 30 (54.5%) 0.040
  100 7 (16.3%) 19 (34.5%)  
  Missing 5 (11.6%) 6 (10.9%)  
 Peritonitis carcinomatosa
  No 40 (93.0%) 46 (83.6%) 0.042
  Yes 0 (0%) 5 (9.1%)  
  Missing 3 (7.0%) 4 (7.3%)  
 Sites of recurrence
  Peritoneal 28 (65.1%) 48 (87.3%) 0.009
  Extra-peritoneal 15 (34.9%) 7 (12.7%)  
 Number of recurrence
  Single 24 (55.8%) 17 (30.9%) 0.013
  Multiple 19 (44.2%) 38 (69.1%)