Table 1 Clinical characteristics of the tertiary debulking surgery (TDS) group and non-TDS group
Characteristics | TDS (n = 43) | Non-TDS (n = 55) | P value |
|---|---|---|---|
Primary | |||
Age, median (range), years | 56.9 (35–74) | 54.2 (27–77) | |
<60 | 24 (55.8%) | 35 (63.6%) | 0.432 |
≧60 | 19 (44.2%) | 20 (36.4%) | |
Cancer | |||
Ovary | 42 (97.7%) | 51 (92.7%) | 0.415 |
Fallopian tube | 0 (0%) | 2 (3.6%) | |
Peritoneum | 1 (2.3%) | 2 (3.6%) | |
FIGO stage | |||
I, II | 10 (23.3%) | 13 (23.6%) | 0.965 |
III, IV | 33 (76.7%) | 42 (76.4%) | |
Histology | |||
Serous | 22 (51.2%) | 36 (65.5%) | 0.333 |
Endometrioid | 6 (14.0%) | 4 (7.3%) | |
Clear cell | 10 (23.3%) | 6 (10.9%) | |
Mucinous | 2 (4.7%) | 3 (5.5%) | |
Others | 3 (7.0%) | 6 (10.9%) | |
CA 125 (U/ml) | |||
< 100 | 10 (23.3%) | 7 (12.7%) | 0.086 |
≧100 | 21 (48.8%) | 38 (69.1%) | |
Missing | 12 (27.9%) | 10 (18.2%) | |
Residual disease at PDS, mm | |||
0 | 34 (79.1%) | 33 (60.0%) | 0.035 |
0-10 | 8 (18.6%) | 11 (20%) | |
≧10 | 1 (2.3%) | 10 (18.2%) | |
Missing | 0 (0%) | 1 (1.8%) | |
Recurrence at SDS | |||
Age, median (range), years | 59.5 (40–76) | 56.8 (32–79) | |
<60 | 20 (46.5%) | 30 (54.5%) | 0.430 |
≧60 | 23 (53.5%) | 25 (45.5%) | |
Platinum-free interval | |||
<6 months | 4 (9.3%) | 3 (5.5%) | 0.09 |
6–12 months | 13 (30.2%) | 9 (16.4%) | |
≧12 months | 22 (51.2%) | 42 (76.4%) | |
Missing | 4 (9.3%) | 1 (1.8%) | |
CA 125 (U/ml) | |||
<100 | 32 (74.4%) | 37 (67.3%) | 0.410 |
≧100 | 8 (18.6%) | 14 (25.5%) | |
Missing | 3 (7.0%) | 4 (7.3%) | |
Peritonitis carcinomatosa | |||
No | 39 (90.7%) | 48 (87.3%) | 0.920 |
Yes | 3 (7.0%) | 4 (7.3%) | |
Missing | 1 (2.3%) | 3 (5.5%) | |
Residual disease at SDS, mm | |||
0 | 38 (88.4%) | 44 (80.0%) | 0.092 |
0–10 | 1 (2.3%) | 8 (14.5%) | |
≧10 | 2 (4.7%) | 1 (1.8%) | |
Missing | 2 (4.7%) | 2 (3.6%) | |
Recurrence at TDS | |||
Age, median (range), years | 61.5 (40–78) | 58.6 (33–80) | |
<60 | 17 (39.5%) | 28 (50.9%) | 0.262 |
≧60 | 26 (60.5%) | 27 (49.1%) | |
CA 125 (U/ml) | |||
<100 | 31 (72.1%) | 30 (54.5%) | 0.040 |
≧100 | 7 (16.3%) | 19 (34.5%) | |
Missing | 5 (11.6%) | 6 (10.9%) | |
Peritonitis carcinomatosa | |||
No | 40 (93.0%) | 46 (83.6%) | 0.042 |
Yes | 0 (0%) | 5 (9.1%) | |
Missing | 3 (7.0%) | 4 (7.3%) | |
Sites of recurrence | |||
Peritoneal | 28 (65.1%) | 48 (87.3%) | 0.009 |
Extra-peritoneal | 15 (34.9%) | 7 (12.7%) | |
Number of recurrence | |||
Single | 24 (55.8%) | 17 (30.9%) | 0.013 |
Multiple | 19 (44.2%) | 38 (69.1%) | |