Skip to main content

Table 3 Multivariate Cox proportional hazards regression analysis

From: Primary tumor location as a predictor of the benefit of palliative resection for colorectal cancer with unresectable metastasis

 

Overall survival

Univariate

Multivariate

Variables

RR (95% CI)

P value

RR (95% CI)

P value

Primary location

0.603 (0.407–0.893)

0.012

0.569 (0.377–0.858)

0.007

T stage

1.384 (0.190–10.062)

0.748

  

LVI

1.182 (0.819–1.708)

0.372

  

PNI

1.456 (0.722–2.937)

0.293

  

N stage

1.123 (0.267–4.717)

1.123

  

Regional LNs

0.981 (0.948–1.016)

0.281

  

Metastasis LNs

1.055 (1.006–1.106)

0.207

  

Sex

1.260 (0.873–1.817)

0.217

  

Diameter of LM

1.766 (1.233–2.530)

0.002

2.622 (1.618–4.248)

0.001

Neo-chemo

1.122 (0.654–1.925)

0.676

  

Histological type

1.733 (1.273–2.357)

0.001

0.194 (0.075–0.501)

0.001

CA199

1.727 (1.209–2.466)

0.003

  

Number of LM

2.330 (1.279–4.246)

0.006

2.134 (1.420–3.205)

0.001

CEA

1.926 (1.309–2.834)

0.001

1.624 (1.054–2.503)

0.028

Systemic chemo

0.738 (0.458–1.190)

0.213

0.582 (0.350–0.968)

0.037

Palliative resection

1.542 (1.065–2.232)

0.022

1.034 (0.973–1.098)

0.285

  1. RR risk ratio, CI confidence interval, LVI lymphovascular invasion, PNI perineural invasion, LNs lymph nodes, LM liver metastasis, Neo-chemo neoadjuvant chemotherapy, Chemo chemotherapy, CEA carcinoembryonic antigen, CA cancer antigen