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Table 3 Stratified analyses of the MPO-463G > A polymorphism on cancer risk by ethnicity and source of control group

From: Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies

Variables A vs. G AA vs. GG AA vs. AG + GG AA + AG vs. GG
OR (95%CI) I 2 OR (95%CI) I 2 OR (95%CI) I 2 OR (95%CI) I 2
 Total 0.90(0.854-1.069) 0.571 0.84(0.76-0.94) 0.417 0.89(0.83-0.95) 0.520 0.87(0.78-0.97) 0.366
Ethnicity
 Caucasian 0.90(0.84–0.97) 0.576 0.85(0.76–0.96) 0.506 0.91(0.84–0.98) 0.533 0.87(0.78–0.98) 0.484
 Asian 0.86(0.75–0.98) 0.597 0.75(0.57–0.98) 0.353 0.84(0.73–0.96) 0.516 0.80(0.61–1.05) 0.242
 Other 1.05(0.86–1.27) 0.000 1.03(0.64–1.67) 0.000 1.08(0.85–1.37) 0.000 0.98(0.61–1.57) 0.000
Lung cancer
 Caucasian 0.956(0.84–0.97) 0.524 1.082(0.888–1.319) 0.573 1.050(0.749–1.472) 0.593 0.950(0.878–1.029) 0.420
 Asian 0.863(0.691–1.078) 0.551 0.641(0.370–1.110) 0.013 0.709(0.400–1.256) 0.000 0.861(0.740–1.002) 0.495
 Other 0.861(0.715–1.037) 0.176 0.567(0.363–0.886) 0.000 0.558(0.360–0.867) 0.000 0.926(0.758–1.132) 0.467
Digestive Cancer
 Caucasian 0.704(0.474–1.045) 0.796 0.609(0.291–1.274) 0.620 0.751(0.514–1.100) 0.428 0.658(0.423–1.024) 0.756
 Asian 0.706(0.537–0.928) 0.613 0.640(0.271–1.512) 0.533 0.785(0.507–1.215) 0.491 0.669(0.512–0.875) 0.474
Resource
 Population 0.91(0.83–0.99) 0.541 0.90(0.77–1.05) 0.453 0.91(0.81–1.01) 0.518 0.91(0.78–1.06) 0.461
 Hospital 0.89(0.81–0.98) 0.603 0.79(0.68–0.93) 0.400 0.88(0.80–0.98) 0.543 0.83(0.71–0.96) 0.301
 Others 0.86(0.69–1.08) 0.625 0.87(0.57–1.33) 0.525 0.86(0.68–1.08) 0.503 0.90(0.59–1.36) 0.111
HWE
 Yes 0.89(0.83–0.96) 0.598 0.88(0.77–0.96) 0.454 0.88(0.81–0.95) 0.507 0.92(0.81–1.04) 0.373
 No 0.91(0.81–1.02) 0.434 0.75(0.61–0.93) 0.167 0.93(0.79–1.10) 0.607 0.74(0.60–0.91) 0.297