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Table 3 Factors associated with the risk of synchronous liver metastasis for stage IV pancreatic cancer (univariate and multivariate logistic regression model) (N = 1080)

From: Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study

Variable

Univariate analysis

Stepwise multivariate analysis

OR

95% CI

P value

OR

95% CI

P value

Age (≥60 vs. <60)

0.94

0.66–1.34

0.7357

   

Sex (male vs. female)

1.29

0.90–1.86

0.1723

   

Smoking (yes vs. no)

1.19

0.83–1.70

0.3371

   

Alcohol (yes vs. no)

1.11

0.65–1.88

0.7058

   

Location (body/tail vs. head/neck)

0.59

0.40–0.89

0.0113

0.55

0.36–0.83

0.0046

Diameter (≥20 vs. <20)

1.60

1.07–2.40

0.0236

1.77

1.16–2.70

0.0082

ALT or AST (elevated vs. normal)

1.78

1.03–3.07

0.0390

1.62

0.92–2.83

0.0923

ALB (low vs. normal)

0.80

0.54–1.19

0.2697

   

CA19-9 (elevated vs. normal)

2.53

1.74–3.68

<0.0001

2.72

1.85–3.99

<0.0001