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Table 2 Comparison of serum tumor marker levels between benign and malignant nodules

From: Combining serum miRNAs, CEA, and CYFRA21-1 with imaging and clinical features to distinguish benign and malignant pulmonary nodules: a pilot study

Serum tumor marker

Benign lung nodules group (n = 19)

Malignant lung nodules group (n = 20)

P value

CYFRA21-1 (ng/ml)

1.90 ± 0.77

4.39 ± 4.91

<0.001

NSE (ng/ml)

17.30 ± 4.39

15.95 ± 4.02

0.324

CEA (ng/ml)

1.08 ± 0.68

2.37 ± 1.97

0.026

miRNA-21-5p

1.99 ± 2.80

6.63 ± 14.40

0.002

miRNA-574-5p

2.59 ± 2.92

86.75 ± 288.25

0.047

  1. Date are presented as means ± SDs. P < 0.05 was considered statistically significant