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Table 1 Comparison of clinical features and imaging features between benign and malignant nodules

From: Combining serum miRNAs, CEA, and CYFRA21-1 with imaging and clinical features to distinguish benign and malignant pulmonary nodules: a pilot study

Characteristic Benign lung nodules group (n = 19) Malignant lung nodules group (n = 20) P value
Clinical
 Age, years 53.11 ± 11.66 63.25 ± 9.48 0.005a
 Male, % 47.37 75.00 0.12c
 Smoking history, % 26.32 70.00 0.01c
 Smoking, cigarettes/year 64.21 ± 131.42 565.00 ± 499.76 0.001a
 Family history of cancer, % 5.26 15.00 0.61c
 Emphysema, % 0.00 25.00 0.04c
Radiological
 Location, %    
  LUL 26.32 25.00  
  LLL 15.79 0  
  RUL 42.10 30.00  
  RLL 15.79 45.00 0.10b
 Diameter, mm 15.21 ± 6.98 21.50 ± 7.06 <0.001a
 Density, %    
  Solid 78.95 65.00  
  Hyaline membrane 10.53 20.00  
  Mixed 10.53 15.00 0.61b
 Lobulation, % 10.53 30.00 0.24c
 Spiculation, % 31.58 70.00 0.03c
 Air bronchogram, % 21.05 20.00 1.00c
 Vessels sign, % 0.00 30.00 0.02c
 Cavitation, % 0.00 20.00 0.11c
 Calcification, % 15.79 0.00 0.11c
 Pleural tail, % 31.58 55.00 0.20c
  1. Data are N (%) or mean ± SD. P < 0.05 was considered statistically significant
  2. LUL left upper lobe, LLL left lower lobe, RUL right upper lobe, RLL right lower lobe
  3. a t test
  4. bchi-square test
  5. cFisher exact test