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Table 1 Comparison of clinical features and imaging features between benign and malignant nodules

From: Combining serum miRNAs, CEA, and CYFRA21-1 with imaging and clinical features to distinguish benign and malignant pulmonary nodules: a pilot study

Characteristic

Benign lung nodules group (n = 19)

Malignant lung nodules group (n = 20)

P value

Clinical

 Age, years

53.11 ± 11.66

63.25 ± 9.48

0.005a

 Male, %

47.37

75.00

0.12c

 Smoking history, %

26.32

70.00

0.01c

 Smoking, cigarettes/year

64.21 ± 131.42

565.00 ± 499.76

0.001a

 Family history of cancer, %

5.26

15.00

0.61c

 Emphysema, %

0.00

25.00

0.04c

Radiological

 Location, %

   

  LUL

26.32

25.00

 

  LLL

15.79

0

 

  RUL

42.10

30.00

 

  RLL

15.79

45.00

0.10b

 Diameter, mm

15.21 ± 6.98

21.50 ± 7.06

<0.001a

 Density, %

   

  Solid

78.95

65.00

 

  Hyaline membrane

10.53

20.00

 

  Mixed

10.53

15.00

0.61b

 Lobulation, %

10.53

30.00

0.24c

 Spiculation, %

31.58

70.00

0.03c

 Air bronchogram, %

21.05

20.00

1.00c

 Vessels sign, %

0.00

30.00

0.02c

 Cavitation, %

0.00

20.00

0.11c

 Calcification, %

15.79

0.00

0.11c

 Pleural tail, %

31.58

55.00

0.20c

  1. Data are N (%) or mean ± SD. P < 0.05 was considered statistically significant
  2. LUL left upper lobe, LLL left lower lobe, RUL right upper lobe, RLL right lower lobe
  3. a t test
  4. bchi-square test
  5. cFisher exact test