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Table 4 DEMs in HCC tissue and their potential target genes

From: Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis

miRNA Adj. P logFC Target genes
hsa-mir-106b 1.94E-41 1.49 ANKRD29, IL1RAP, ADARB1, ARID4B, EPHA4, FBXL5, PDCD1LG2, PKD2, PTPN4, SLC40A1
hsa-mir-148b 9.59E-22 1.37 ESR1, ABCB7, B4GALT6, CDK19, LDLR, MXD1, NPTN, RPS6KA5, SOS2, SZRD1
hsa-mir-151 2.61E-21 1.14 AGO2, ZFAND5, CLK1, AQP4, CASD1, RPS6KA5, FAM104A, NAA15, YTHDF3, HIF1A
hsa-mir-221 7.37E-21 1.66 ESR1, FOS, CXCL12, CDKN1B, GABRA1, PANK3, TCF12, HECTD2, RFX7, TMCC1
hsa-mir-18a 2.16E-20 2.48 ESR1, NEDD9, BBX, INADL, MAP7D1, PHF19, RORA, ZBTB47, CDK19, DICER1
hsa-mir-200b 4.50E-17 −3.15 MAGEC2, ESM1, TCEB1, TRIM33, LHFP, PTPN21, ARHGAP6, VASH2, HIPK3, NR5A2
hsa-mir-224 4.85E-15 −71.38 NRCAM, CPNE8, ZNF207, ACSL4, RNF144B, SH3KBP1, RNF38, SLC4A4, GPR158, GGNBP2
hsa-mir-200a 5.03E-14 −2.29 COL15A1, MYBL1, ZEB2, ATP8A1, DCP2, TMEM170B, ZBTB34, DUSP3, TRHDE, RSAD2
hsa-mir-182 1.41E-06 −2.69 NRCAM, ABHD13, MFAP3, PCNX, NADK2, CAMSAP2, SLC39A9, NCALD, ANK3, HOXA9
hsa-mir-142-5p 6.59E-06 −1.49 ANKRD29, IGF2BP3, IGSF3, ZFP36, ZFPM2, BAI3, AFF4, DIAPH2, AHR, ARID4B
  1. Adj. P: adjusted P value, FC: fold change
  2. Positive logFC values denote up-regulated miRNAs, while negative logFC values denote down-regulated miRNAs. If there were more than ten genes predicted by miRDB, only ten genes were listed in the table