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Table 2 Hub genes and their related DEMs

From: Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis

Gene symbol

Node degree

Related DEMs

TOP2A

30

none

FOS

27

hsa-miR-221

TK1

24

none

CDC20

23

none

ESR1

21

hsa-miR-148b, hsa-miR-221, hsa-miR-18a, hsa-miR-181b, hsa-miR-19a

CCNB2

18

none

CXCL12

17

hsa-miR-221

FOXO1

16

hsa-miR-135b, hsa-miR-324-3p, hsa-miR-369-3p

HMMR

15

none

VWF

15

none

ACSM3

14

none

COL4A1

14

none

ZIC2

14

none

RFC4

13

none

TXNRD1

13

none

GNAO1

12

hsa-miR-193a

CYP3A4

10

none

RAP2A

10

none

  1. Only top 18 DEGs with higher node degrees were showed in this table. Node degree: the number of edges incident to the node; Related miRNAs: miRNAs may potentially target the gene