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Table 5 Association between CRP and clinicopathologic parameters in subsites other than tongue and buccal mucosa (n = 85)

From: Roles of preoperative C-reactive protein are more relevant in buccal cancer than other subsites

Characteristic

CRP

p value

Negative

Positive

Pathologic tumor status

 Early (T1–T2) (n = 43)

38

(88.4%)

5

(11.6%)

0.001

 Advanced (T3–T4) (n = 42)

24

(57.1%)

18

(42.9%)

 

Pathologic N stage

 N0 (n = 54)

40

(74.1%)

14

(25.9%)

0.277

 N1 (n = 14)

8

(57.1%)

6

(42.9%)

0.765a

 N2 (n = 17)

14

(82.4%)

3

(17.6%)

 

Nodal status

 (−) metastasis, (−) ECS (n = 54)

40

(74.1%)

14

(25.9%)

0.915

 (+) metastasis, (−) ECS (n = 15)

11

(73.3%)

4

(26.7%)

0.694a

 (+) metastasis, (+) ECS (n = 16)

11

(68.8%)

5

(31.2%)

 

Differentiation

 Well (n = 26)

21

(80.8%)

5

(19.2%)

0.425

 Moderate (n = 49)

35

(71.4%)

14

(28.6%)

0.195a

 Poor (n = 10)

6

(60.0%)

4

(40.0%)

 

Tumor stage

 Early (I–II) (n = 30)

27

(90.0%)

3

(10.0%)

0.009

 Advanced (III–IV) (n = 55)

35

(63.6%)

20

(36.4%)

 

Skin invasion

 No (n = 77)

57

(74.0%)

20

(26.0%)

0.677a

 Yes (n = 8)

5

(62.5%)

3

(37.5%)

 

Nerve invasion

 No (n = 66)

48

(72.7%)

18

(27.3%)

0.934

 Yes (n = 19)

14

(73.7%)

5

(26.3%)

 

Blood vessel invasion

 No (n = 79)

59

(74.7%)

20

(25.3%)

0.337a

 Yes (n = 6)

3

(50.0%)

3

(50.0%)

 

Lymphatic invasion

 No (n = 83)

60

(72.3%)

23

(27.7%)

0.383

 Yes (n = 2)

2

(100.0%)

0

(0.0%)

 

Tumor depth ≥10 mm

 No (n = 42)

36

(85.7%)

6

(14.3%)

0.009

 Yes (n = 43)

26

(60.5%)

17

(39.5%)

 

Bone invasion

 No (n = 54)

47

(87.0%)

7

(13.0%)

<0.001

 Yes (n = 31)

15

(48.4%)

16

(51.6%)

 
  1. ECS extracapsular spread
  2. aχ2 trend test
  3. † Fisher’s exact test