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Table 2 Relationship between TUFM and p53 expression and clinicopathological parameters in colorectal adenomas

From: Expression and clinicopathologic significance of TUFM and p53 for the normal–adenoma–carcinoma sequence in colorectal epithelia

Variables TUFM P value p53 P value
+ +
Gender
 Male 46 68 P = 0.486 26 88 P = 0.801
 Female 20 23   9 34  
Age (years)
 <45 9 13 P = 0.923 4 18 P = 0.717
 45 ≤ n < 60 26 33   12 47  
n ≥ 60 31 45   19 57  
Tumor size (cm)
d < 1 cm 39 64 P = 0.083 16 87 P = 0.001
 1 cm ≤ d < 2 cm 13 19   6 26  
d ≥ 2 cm 14 8   13 9  
Number of tumor
n = 1 45 67 P = 0.456 24 88 P = 0.681
n ≥ 2 21 24   11 34  
Location
 Left sidea 35 58 P = 0.115 21 72 P = 0.883
 Right sideb 20 27   11 36  
 Both sides 11 6   3 14  
Histological type
 Tubular 34 68 P = 0.028 14 88 P = 0.001
 Villous 15 11   14 12  
 Tubulovillous 12 8   5 15  
 Serrated 5 4   2 7  
Dysplasia
 Mild 28 64 P = 0.001 0 92 P = 0.001
 Moderate 7 11   3 15  
 Severe 31 16   32 15  
  1. P < 0.05, statistically significant
  2. aThe left side comprises the splenic flexture, descending and sigmoid colon, and rectum
  3. bThe right side comprises the cecum, ascending colon, hepatic flexure, and transverse colon