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Table 2 Prognostic factors for disease-specific survival (DSS) in univariable and multivariable Cox proportional hazards regression models

From: TPX2 expression is associated with poor survival in gastric cancer

 

Univariate (log-rank)

Multivariate

 
 

5-year DSS (%)

p value

HR

95% CI

p value

Gender

 Male

72.3

    

 Female

74.6

0.891

   

Age

 <65

78.8

 

1

  

 ≥65

68.1

0.025

1.42

0.90 to 2.26

0.136

Pathological type

 Differentiated

82.0

 

1

  

 Undifferentiated

65.4

0.004

1.32

0.82 to 2.12

0.253

Main location

 Middle or lower

76.1

 

1

  

 Upper

59.7

0.026

1.52

0.94 to 2.47

0.089

Depth of invasion

 T1

97.4

 

1

  

 T2-T4

56.0

<0.001

7.66

2.71 to 21.6

<0.001

LN metastasis

 Negative

94.5

 

1

  

 Positive

50.0

<0.001

6.40

3.10 to 13.2

<0.001

TPX2

 Low

78.1

 

1

  

 High

65.9

0.004

1.05

0.66 to 2.26

0.840

  1. DSS disease-free survival, TPX2 targeting protein for Xenopus kinesin-like protein 2, LN lymph node