Dedifferentiated endometrioid carcinoma of the uterus : report of four cases and review of literature

Table 2 Results of immunohistochemical stains of the four cases

IHC stain	Case 1		Case 2		Case 3		Case 4
IHC stain	UC	DC	UC	DC	UC	DC	UC	DC
CK 8/18	Diffuse, perinuclear dot-like	Diffuse, cytoplasmic	Diffuse, perinuclear dot-like, and cytoplasmic	Diffuse, cytoplasmic	Negative	Diffuse, cytoplasmic	Focal, perinuclear dot-like, and cytoplasmic	Diffuse, cytoplasmic
Pancytokeratin	Diffuse, perinuclear dot-like	Diffuse, cytoplasmic	Diffuse, perinuclear dot-like < cytoplasmic	Diffuse, cytoplasmic	Focal, perinuclear dot-like < cytoplasmic	Diffuse, cytoplasmic	Focal, perinuclear dot-like < cytoplasmic	Diffuse, cytoplasmic
EMA	Negative	Diffuse, cytoplasmic	Diffuse, perinuclear dot-like, and cytoplasmic	Diffuse, cytoplasmic	Focal, perinuclear dot-like, and cytoplasmic	Diffuse, cytoplasmic	Focal, perinuclear dot-like, and cytoplasmic	Diffuse, cytoplasmic
Vimentin	Focal	Negative	Diffuse	Diffuse	Diffuse	Diffuse	Diffuse	Focal
ER	Negative	Positive	Negative	Positive	Negative	Negative	Negative	Positive
PR	Negative	Positive	Negative	Positive	Negative	Negative	Negative	Positive
E-cadherin	Negative	Diffuse	Negative	Focal	Negative	Diffuse, weakly	Negative	Diffuse
PAX-8	Negative	Diffuse	Negative	Diffuse	Negative	Diffuse	Diffuse	Diffuse

Proportion of tumor cells are >50%, diffuse; 10 ~ 50%, focal; <10%, negative; EMA epithelial membrane antigen; ER estrogen receptor; PR progesterone receptor

ISSN: 1477-7819