Table 3 Univariate and multivariate analyses of prognostic factors for survival

Age

≥75

<75

1.8 (0.25–13.7)

0.54

Gender

Male

Female

1.1 (0.45–2.9)

0.78

ECOG performance status

0–1

2–4

1.4 (0.57–3.4)

0.48

1.1 (0.41–2.8)

0.88

Bone pain

Absent

Present

2.0 (0.90–4.5)

0.091

2.7 (0.93–8.1)

0.068

Histologic type

Undifferentiated

Differentiated

1.1 (0.53–2.5)

0.73

Stage^a

I–III

IV

1.0 (0.46–2.2)

0.99

Pattern of bone metastasis

Synchronous

Metachronous

2.8 (1.1–7.5)

0.038

3.6 (1.1–11.7)

0.035

Extraosseous metastasis

Absent

Present

1.1 (0.47–2.8)

0.77

4.1 (1.2–14.9)

0.028