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Table 3 Univariate and multivariate analyses of prognostic factors for survival

From: Clinical outcomes and prognostic factors for gastric cancer patients with bone metastasis

   Univariate analysis Multivariate analysis
RR (95% CI) p value RR (95% CI) p value
Age ≥75     
<75 1.8 (0.25–13.7) 0.54   
Gender Male     
Female 1.1 (0.45–2.9) 0.78   
ECOG performance status 0–1     
2–4 1.4 (0.57–3.4) 0.48 1.1 (0.41–2.8) 0.88
Bone pain Absent     
Present 2.0 (0.90–4.5) 0.091 2.7 (0.93–8.1) 0.068
Histologic type Undifferentiated     
Differentiated 1.1 (0.53–2.5) 0.73   
Stagea I–III     
IV 1.0 (0.46–2.2) 0.99   
Pattern of bone metastasis Synchronous     
Metachronous 2.8 (1.1–7.5) 0.038 3.6 (1.1–11.7) 0.035
Extraosseous metastasis Absent     
Present 1.1 (0.47–2.8) 0.77 4.1 (1.2–14.9) 0.028
  1. Abbreviations: CI confidential interval, ECOG Eastern Cooperative Oncology
  2. aStage was according to the 14th edition of the Japanese classification of gastric carcinoma