Table 1 Clinicopathologic characteristics of patients with adenocarcinoma of the EGJ and the upper third of the stomach
Variable | Value |
|---|---|
Age in years, median (range) | 60 (21–85) |
Sex | |
Male | 488 (72.6%) |
Female | 184 (27.4%) |
Tumor location | |
Siewert 2 | 90 (13.4%) |
Siewert 3 | 211 (31.4%) |
Upper third | 371 (55.2%) |
Tumor size in cm, median (range) | 4.7 (0.2–20.5) |
Gross appearance | |
I | 13 (1.9%) |
IIa/IIb/IIc | 262 (39.0%) |
III | 6 (0.9%) |
B1 | 18 (2.7%) |
B2/B3 | 373 (55.5%) |
Differentiation | |
Differentiated | 270 (40.2%) |
Undifferentiated | 402 (59.8%) |
Lauren’s classification | |
Intestinal | 333 (49.6%) |
Diffuse | 265 (39.4%) |
Mixed | 72 (10.7%) |
Not evaluated | 2 (0.3%) |
T stage | |
T1 | 277 (41.2%) |
T2 | 100 (14.9%) |
T3 | 201 (29.9%) |
T4a | 80 (11.9%) |
T4b | 14 (2.1%) |
Number of harvested lymph nodes, median (range) | 28 (15–82) |
N stage | |
0 | 424 (63.0%) |
1 | 98 (14.6%) |
2 | 77 (11.5%) |
3 | 73 (10.9%) |
TNM Stage | |
1 | 338 (50.3%) |
2 | 179 (26.6%) |
3 | 155 (23.1%) |
Proximal resection margin, median (cm) | 2.0 (0.1–10.5) |
Lymphovascular invasion | |
Identified | 207 (30.8%) |
Not identified | 464 (69.1%) |
Not evaluated | 1 (0.1%) |
Perineural invasion | |
Identified | 175 (26.0%) |
Not identified | 483 (71.9%) |
Not evaluated | 14 (2.1%) |
Adjuvant chemotherapy | |
Yes | 312 (46.4%) |
No | 360 (53.6%) |