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Table 2 Univariate analysis of overall survival in patients with KTs of colorectal origin

From: Clinical analysis of Krukenberg tumours in patients with colorectal cancer—a review of 57 cases

  Median 95% confidence interval P value (log-rank)
Age at diagnosis of KT 0.979
 <60 years 36 27.546, 44.454
 ≥60 years 31 26.394, 35.606
Menses 0.425
 Pre-menopausal 35 27.302, 42.698
 Post-menopausal 38 26.016, 49.984
Timing of ovarian metastases 0.027
 Synchronous 31 3.592, 58.408
 13–24 months 35 28.196, 41.804
 >24 months 54 37.622, 70.378
Tumour size 0.256
 ≤10 cm 36 30.511, 41.489
 >10 cm 20 2.402, 37.598
Status of ovarian involvement 0.570
 Unilateral 35 25.783, 44.217
 Bilateral 36 25.828, 46.172
Extent of metastatic disease <0.001
M ovary 54 35.028, 72.972
 M1 35 20.868, 49.132
 M2 13 10.608, 15.392
Extent of surgery 0.224
 Minimal 32 12.493,51.507
 Extensive 38 29.071, 46.929
Completeness of cytoreduction <0.001
 CC0 56 46.082, 58.200
 CC1 28 10.066, 45.934
 CC2 13 7.951, 18.049
Systemic chemotherapy 0.006
 Yes 47 34.992, 59.008
 No 30 8.932, 51.068
Depth of tumour invasion 0.117
 T3 39 33.234, 44.766
 T4 30 15.296, 44.704
Lymph node metastasis 0.011
 Retroperitoneal lymph node metastasis 18 9.363, 26.637
 Non-retroperitoneal lymph node metastasis 36 19.390, 58.610
 None 39 27.484, 50.516
  1. Note: CC0 and CC1 are described as complete cytoreduction, CC2 as incomplete cytoreduction
  2. CC0 no macroscopic residual tumour, CC1 maximal diameter of residual tumour <2.5 mm, CC2 maximal diameter of residual tumour ≥2.5 mm, M ovary ovary-only metastasis, M1 metastasis confined to the pelvis, M2 metastasis beyond the pelvis