Table 2 Univariate analysis of overall survival in patients with KTs of colorectal origin
From: Clinical analysis of Krukenberg tumours in patients with colorectal cancer—a review of 57 cases
Median | 95% confidence interval | P value (log-rank) | |
|---|---|---|---|
Age at diagnosis of KT | 0.979 | ||
<60 years | 36 | 27.546, 44.454 | |
≥60 years | 31 | 26.394, 35.606 | |
Menses | 0.425 | ||
Pre-menopausal | 35 | 27.302, 42.698 | |
Post-menopausal | 38 | 26.016, 49.984 | |
Timing of ovarian metastases | 0.027 | ||
Synchronous | 31 | 3.592, 58.408 | |
13–24 months | 35 | 28.196, 41.804 | |
>24 months | 54 | 37.622, 70.378 | |
Tumour size | 0.256 | ||
≤10 cm | 36 | 30.511, 41.489 | |
>10 cm | 20 | 2.402, 37.598 | |
Status of ovarian involvement | 0.570 | ||
Unilateral | 35 | 25.783, 44.217 | |
Bilateral | 36 | 25.828, 46.172 | |
Extent of metastatic disease | <0.001 | ||
M ovary | 54 | 35.028, 72.972 | |
M1 | 35 | 20.868, 49.132 | |
M2 | 13 | 10.608, 15.392 | |
Extent of surgery | 0.224 | ||
Minimal | 32 | 12.493,51.507 | |
Extensive | 38 | 29.071, 46.929 | |
Completeness of cytoreduction | <0.001 | ||
CC0 | 56 | 46.082, 58.200 | |
CC1 | 28 | 10.066, 45.934 | |
CC2 | 13 | 7.951, 18.049 | |
Systemic chemotherapy | 0.006 | ||
Yes | 47 | 34.992, 59.008 | |
No | 30 | 8.932, 51.068 | |
Depth of tumour invasion | 0.117 | ||
T3 | 39 | 33.234, 44.766 | |
T4 | 30 | 15.296, 44.704 | |
Lymph node metastasis | 0.011 | ||
Retroperitoneal lymph node metastasis | 18 | 9.363, 26.637 | |
Non-retroperitoneal lymph node metastasis | 36 | 19.390, 58.610 | |
None | 39 | 27.484, 50.516 | |