Table 2 Univariate and multiple Cox proportional hazard analysis between clinical and pathological variables with PTC recurrence

 Low × high

1.67(0.38–7.64)

0.389

 Low × intermediate

0.87(0.29–3.35)

0.879

 Intermediate × high

3.34(1.42–6.75)

0.087

 Low × high

1.67(0.77–3.98)

0.196

 Low × intermediate

2.12(0.78–5.86)

0.132

 Intermediate × high

1.45(0.52–3.88)

0.243

Primary tumor size

5.14(3.14–11.64)

0.009*

1.54(0.43–7.67)

0.567

 I/II × III/IV

4.31(2.01–9.87)

0.011*

2.68(1.10–6.72)

0.067

Extrathyroid extension

2.12(0.78–6.81)

0.021*

2.53(0.54–12.42)

0.314

Cervical lymph node metastasis

2.85(0.76–6.12)

0.107

 miR-21

2.01(0.33–5.43)

0.132

 miR-9

1.32(0.54–4.53)

0.225

 miR-146b

1.11(0.24–4.13)

0.682

 miR-220

1.13(0.45–4.14)

0.745

 miR-221

1.46(1.20–1.88)

0.001*

1.41(1.14–1.95)

0.007*

 miR-222

2.81(1.11–7.21)

0.021*

1.86(0.76–5.65)

0.226