Table 2 Prognostic factors for DSS on multivariate analysis in DGC
Univariate (log-rank) | Multivariate | ||||
|---|---|---|---|---|---|
5-yr DSS (%) | p | HR | 95% CI | p | |
Age (years) | |||||
< 65 | 73 | 1 | |||
≥ 65 | 51 | 0.013 | 1.4 | 0.71-2.6 | 0.36 |
Gender | |||||
Female | 70 | ||||
Male | 61 | 0.52 | |||
Main location | |||||
Middle or lower | 72 | 1 | |||
Upper | 41 | 0.010 | 1.8 | 0.90–3.4 | 0.097 |
Depth of invasion | |||||
Early (T1) | 97 | 1 | |||
Advanced (T2/3/4) | 49 | <0.001 | 8.9 | 1.2-68 | 0.034 |
LN metastasis | |||||
Negative (N0) | 95 | 1 | |||
Positive (N1/2/3) | 43 | <0.001 | 6.1 | 1.8–21 | 0.004 |
FGFR1 | |||||
Low | 74 | 1 | |||
High | 50 | 0.009 | 1.2 | 0.60–2.3 | 0.66 |
FGFR2 | |||||
Low | 80 | 1 | |||
High | 48 | 0.001 | 1.5 | 0.69–3.1 | 0.32 |
FGFR3 | |||||
Low | 65 | ||||
High | 65 | 0.66 | |||
FGFR4 | |||||
Low | 86 | 1 | |||
High | 60 | 0.023 | 1.1 | 0.32–3.7 | 0.89 |