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Table 2 Univariate analysis of potential prognostic factors for OS and CSS

From: Cytoreductive nephrectomy with thrombectomy before targeted therapy improves survival for metastatic renal cell carcinoma with venous tumor thrombus: a single-center experience

 

Univariate for OS

Univariate for CSS

Variables

HR(95% CI)

P value

HR(95% CI)

P value

Age (≥60 vs. <60)

1.56(0.82–2.96)

0.178

1.53(0.73–3.21)

0.256

Gender (female vs. male)

1.02(0.48–2.17)

0.958

1.07(0.45–2.51)

0.883

ECOG PS (1 vs. 0)

0.59(0.29–1.20)

0.145

0.64(0.29–1.41)

0.267

Pathological type (non-clear cell vs. clear cell)

0.71(0.28–1.83)

0.480

0.76(0.26–2.18)

0.605

Nuclear grade (G3 + G4 vs. G1 + G2)

0.84(0.43–1.64)

0.608

0.65(0.31–1.40)

0.273

VT level (above hepatic vein vs. below hepatic vein)

1.67(0.71–3.03)

0.302

1.36(0.58–3.20)

0.482

T stage (T4 vs. T3)

1.50(0.70–3.20)

0.294

1.63(0.69–3.87)

0.264

N stage (N1 vs. N0)

1.32(0.69–2.54)

0.407

1.63(0.77–3.47)

0.203

Number of metastatic sites (more than 1 vs. 1)

2.94(1.41–6.09)

0.004

2.14(0.86–5.34)

0.103

Combined therapy

    

 TMT alone

2.69(1.20–6.02)

0.017

3.25(1.28–8.27)

0.013

 Surgery alone

5.64(2.39–13.29)

<0.001

7.05(2.60–19.11)

<0.001