Table 4 Univariate and multivariate analyses for overall survival

 <50 (vs. ≥50)

1.20 (0.76–1.89)

0.436

 Bone (vs. soft tissue)

1.32 (0.77–2.27)

0.318

Primary site

0.633

 Trunk (vs. extremities)

0.85 (0.43–1.68)

0.639

 Retroperitoneum (vs. extremities)

0.65 (0.31–1.37)

0.259

 Visceral (vs. extremities)

1.15 (0.56–2.35)

0.702

Histological subtype

0.002

 UPS (vs. leiomyosarcoma)

1.24 (0.55–2.81)

0.608

 Others (vs. leiomyosarcoma)

2.54 (1.46–4.42)

0.001

Prior chemotherapy

0.126

 Second-line (vs. first-line)

1.38 (0.72–2.65)

0.332

 Third-or-greater line (vs. first-line)

1.90 (1.00–3.62)

0.052

 SD/PD (vs. CR/PR)

3.81 (1.37–10.55)

0.010

Multivariate analysis

Factors

HR (95% CI)

p value

 ≥50 (vs. <50)

 Bone (vs. soft tissue)

 Trunk (vs. extremities)

 Retroperitoneum (vs. extremities)

 Visceral (vs. extremities)

 UPS (vs. leiomyosarcoma)

 Others (vs. leiomyosarcoma)

 Second-line (vs. first-line)

 Third-or-greater line (vs. first-line)

 SD/PD (vs. CR/PR)

3.99 (1.42–11.22)

0.009