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Table 5 Subgroup analysis stratified by smoke status

From: Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population

Genotype No. of cases (%) No. of controls (%) ORa (95% CI) P value
−149C>T     
Smokers     
TT 23 (5.1) 15 (5.6) 0.81 (0.84 2.35) 0.571
CT 135 (29.4) 95 (35.5) 0.74 (0.45 1.83) 0.469
CC 300 (65.5) 158 (58.9) Reference  
CT+TT 158 (34.5) 110 (41.1) 0.76 (0.52 1.17) 0.274
Non-smokers     
TT 19 (8.5) 16 (4.9) 1.59 (0.37 1.94) 0.371
CT 62 (27.4) 124 (37.1) 0.69 (0.24 1.64) 0.108
CC 145 (64.1) 194 (58.0) Reference  
CT+TT 81 (35.9) 140 (42) 0.77 (0.49 1.25) 0.251
−2437T>A     
Smokers     
AA 47 (51.9) 31 (51.6) 1.53 (0.42 1.97) 0.473
TA 173 (37.8) 98 (36.7) 1.78 (0.35 1.67) 0.082
TT 138 (10.2) 139 (11.7) Reference  
TA+AA 220 (89.7) 129 (88.3) 1.72 (0.68 1.49) 0.627
Non-smokers     
AA 35 (47.9) 29 (47.8) 0.71 (0.34 1.68) 0.376
TA 204 (44.4) 111 (41.5) 1.07 (0.32 1.85) 0.723
TT 219 (7.7) 128 (10.7) Reference  
TA+AA 239 (92.3) 140 (89.3) 1.00 (0.64 1.59) 0.504
  1. OR odds ratio, CI confidence interval
  2. aAdjusted for age and sex in a logistic regression model