Fig. 4From: Risks and benefits of combining denosumab and surgery in giant cell tumor of bone—a case seriesHistologic appearance after denosumab treatment. Histologic appearance of denosumab-treated giant cell tumor of bone. The residual tumor is composed of bland spindle cells organized in short fascicles, associated with collagen matrix production. No osteoclast-like multinucleated giant cells are presentBack to article page