Table 4 Acute and late adverse events due to treatment
From: Radiation field size and dose determine oncologic outcome in esophageal cancer
| Â | Pre-CRT | Def-CRT | p value | |||
|---|---|---|---|---|---|---|
G3 | G4 | G3 | G4 | |||
Acute toxicity | Esophagitis | 3 | 2 | 10 | 3 | 0.66 |
Leukopenia | 3 | 1 | 5 | 1 | 0.72 | |
Neutropenia | 3 | 1 | 3 | – | 0.21 | |
Anemia | 2 | 1 | 7 | 2 | 0.74 | |
Thrombocytopenia | 2 | – | 4 | 1 | 1 | |
Nausea | 4 | – | 3 | – | 0.21 | |
Vomiting | 1 | – | 6 | – | 0.41 | |
Febrile neutropenia | 1 | – | 2 | – | 1 | |
Total events | n = 8 | n = 5 | n = 24 | n = 5 | 0.55 | |
Late toxicity | Cardiac | 3 | – | 4 | – | 0.68 |
Pulmonary | 4 | – | 2 | – | 0.17 | |
Esophageal (stricture) | 12 | 1 | 6 | – | <0.001 | |
Total events | n = 16 | n = 1 | n = 12 | n = 0 | <0.001 | |