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Table 3 The pathways enriched for the differentially expressed genes

From: Microarray data analysis to identify crucial genes regulated by CEBPB in human SNB19 glioma cells

KEGG ID

Name

Gene number

p value

Gene symbols

(A)

 4062

Chemokine signaling pathway

12

1.63E−03

PTK2, PIK3R2, GNG10, GNG5, RAP1B, PIK3R1, NRAS, IL8, GNG12, CSK, FOXO3, CCL2

 4510

Focal adhesion

11

7.54E−03

PTK2, PIK3R2, THBS1, THBS2, RAP1B, PPP1CC, PIK3R1, ITGB1, ACTG1, FLNB, CAV2

 4810

Regulation of actin cytoskeleton

11

1.18E−02

PTK2, PIK3R2, CYFIP2, PPP1CC, PIK3R1, NRAS, ITGB1, GNG12, ACTG1, CSK, ARHGEF6

 4910

Insulin signaling pathway

9

5.22E−03

PIK3R2, PPP1CC, PIK3R1, NRAS, SOCS2, PTPN1, PYGB, CALM2, PTPRF

 3013

RNA transport

9

9.27E−03

PABPC1, EIF3A, NUP54, EIF3G, UPF3B, NUP155, KPNB1, NUP37, EIF2S3

 4145

Phagosome

8

2.82E−02

TAP1, THBS1, THBS2, ATP6V1G1, ITGB1, ACTG1, LAMP2, DYNC1LI2

 5100

Bacterial invasion of epithelial cells

7

1.24E−03

PTK2, PIK3R2, PIK3R1, ITGB1, RHOG, ACTG1, CAV2

 5142

Chagas disease (American trypanosomiasis)

7

1.13E−02

PIK3R2, SERPINE1, GNA11, PIK3R1, IL8, IFNGR1, CCL2

 4722

Neurotrophin signaling pathway

7

3.05E−02

PIK3R2, RAP1B, PIK3R1, NRAS, CALM2, CSK, FOXO3

 4360

Axon guidance

7

3.28E−02

PTK2, DPYSL2, SEMA4F, NRAS, ITGB1, SLIT2, EFNA1

5131

Shigellosis

6

3.01E−03

ITGB1, IL8, RHOG, ACTG1, FBXW11, CSK

 5211

Renal cell carcinoma

5

2.45E−02

PIK3R2, RAP1B, PIK3R1, NRAS, EPAS1

 5412

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

5

3.03E−02

ITGB1, DAG1, GJA1, ACTG1, CDH2

 5410

Hypertrophic cardiomyopathy

5

4.62E−02

TPM3, ITGB1, DAG1, TPM1, ACTG1

 4350

TGF-beta signaling pathway

5

4.83E−02

THBS1, THBS2, SMAD6, ID3, SMAD5

 20

Citrate cycle (TCA cycle)

4

5.11E−03

CS, DLD, DLAT, SDHA

5144

Malaria

4

3.19E−02

THBS1, THBS2, IL8, CCL2

 5213

Endometrial cancer

4

3.39E−02

PIK3R2, PIK3R1, NRAS, FOXO3

 5223

Non-small cell lung cancer

4

3.82E−02

PIK3R2, PIK3R1, NRAS, FOXO3

 3410

Base excision repair

3

4.23E−02

POLB, PARP1, PARP3

(B)

 4144

Endocytosis

9

4.62E−04

ASAP2, VPS36, TGFBR2, ASAP1, CAV1, SH3KBP1, EHD1, RAB22A, DNM3

 4142

Lysosome

7

4.55E−04

CTSD, TPP1, ATP6V0A1, ABCB9, AP1S1, AP1S2, NEU1

 2010

ABC transporters

4

1.58E−03

ABCC2, ABCC3, ABCB9, ABCC5

 10

Glycolysis/gluconeogenesis

4

6.56E−03

ENO2, ALDH3A2, PGAM1, PGK1

 5220

Chronic myeloid leukemia

4

9.85E−03

TGFBR2, CCND1, CDKN1A, BCL2L1

 561

Glycerolipid metabolism

3

1.98E−02

ALDH3A2, AGPAT9, LCLAT1

 5212

Pancreatic cancer

3

4.69E−02

TGFBR2, CCND1, BCL2L1

 4966

Collecting duct acid secretion

2

3.85E−02

ATP6V1D, ATP6V0A1

  650

Butanoate metabolism

2

4.67E−02

AKR1B10, HMGCS1

  1. (A) The pathways enriched for the up-regulated genes. (B) The pathways enriched for the down-regulated genes. Kyoto Encyclopedia of Genes and Genomes, KEGG; identification, ID