Skip to main content

Table 8 Discordance of hormonal receptor and HER2 status between primary and metastatic samples (only in patients with rebiopsies and with diagnoses confirmed by pathologist; n = 80)

From: Factors that predict recurrence later than 5 years after initial treatment in operable breast cancer

 

Change of HR and/or HER2 status

Early recurrence (n = 40)

Late recurrence (n = 40)

No change ER status

36

36

ER change

Pos → neg

2

2

Neg → pos

2

2

No change PR status

35

37

PR change

Pos → neg

2

2

Neg → pos

3

1

No change HER2 status

35

38

HER2 change

Pos → neg

1

0

Neg → pos

4

2

  1. Changes were seen in 17 patients (some patients had more than 1 biomarker changed)