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Table 2 Subgroup analysis of effects of BRAF mutation on aggressive clinicopathological features and poor prognosis of PTC according to ethnics

From: Associations between BRAFV600E and prognostic factors and poor outcomes in papillary thyroid carcinoma: a meta-analysis

Subgroup OR OR (95 % CI) I 2 (%) Model used
Extrathyroidal invasion
Asian (23 studies) 1.84 1.53–2.22 58 Random-effects
Caucasian (26 studies) 1.19 1.69–2.84 74 Random-effects
TNM stage
Asian (20 studies) 1.69 1.34–2.14 56 Random-effects
Caucasian (30 studies) 1.72 1.28–2.32 78 Random-effects
Lymph node metastasis
Asian (27 studies) 1.25 1.06–1.49 58 Random-effects
Caucasian (30 studies) 1.54 1.19–1.98 77 Random-effects
Recurrence
Asian (6 studies) 1.30 1.01–1.68 80 Random-effects
Caucasian (18 studies) 2.48 2.06–2.98 73 Random-effects
  1. OR odds ratio, RR risk ratio, CI confidence interval