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Table 2 Postoperative outcomes following APR for anal cancer, compared by HIV infection status

From: Outcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review

 

HIV−

HIV+

P

HIV− >60

Total N

1417

308

–

1611

 

N (%)

N (%)

 

N (%)

Postoperative complications

 Renal

106 (7.5 %)

28 (9.1 %)

0.66

154 (9.6 %)

 Cardiac

≤10 (<1 %)

≤10 (<3 %)

0.38

68 (4.2 %)

 Respiratory

221 (15.6 %)

56 (17.8 %)

0.67

258 (16.0 %)

 Liver

0

0

0

0

 Gastrointestinal

15 (1.0 %)

0

0.43

29 (1.8 %)

 Venous thromboembolism

16 (1.2 %)

0

0.42

30 (1.8 %)

 Wound infection and intra-abdominal infection

200 (14.1 %)

39 (12.5 %)

0.74

209 (13.0 %)

 Sepsis

40 (2.8 %)

≤10 (<3 %)

0.40

71 (4.4 %)

 Postoperative hemorrhage

19 (1.4 %)

16 (5.1 %)

0.05

46 (2.8 %)

 Re-exploration

0

0

0

0

 Any complication

447 (31.5 %)

107 (34.7 %)

0.62

613 (38.1 %)

 In-hospital mortality

21 (1.5 %)

0 (0 %)

0.36

46 (2.9 %)

Length of staya

 Median (IQR)

8(6–12)

9(7–14)

0.13

9(7–14)

 Extended LOS

423(29.8 %)

114 (36.9 %)

0.26

644(40.0 %)

Costb

 Median (IQR)

20,124 (13,529–29,264)

23,908 (15,915–34,378)

0.08

19,618 (13,822–23,757)

 Mean (95 % CI)

26,588 (23,169–30,008)

29,899 (23,115–36,683)

0.39

27,948 (25,035–30,861)

  1. Small sample subsets that are non-zero but less than 11 patients are not reportable per HCUP NIS guidelines
  2. aExtended LOS: more than10 days (based on the 75th percentile of the data)
  3. bAdjusted for 2011$. Total N for costs HIV− = 1212; HIV+ = 252; HIV− >60 = 1363