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Table 1 Univariate analysis of the prognostic factors affecting survival

From: Factors associated with improved survival following surgical treatment for metastatic prostate cancer in the spine: retrospective analysis of 29 patients in a single center

Factor

Number

P (log-rank test)

Age

  

 <65/≥65

8/21

0.128

Location

  

 Cervical/thoracic/lumbar/sacral

5/11/12/1

0.306

 Junctional/mobile spine/semirigid/rigid

8/13/8/0

0.464

Karnofsky performance status

  

 100–80/70–50/40–10

3/17/9

0.071

 100–80/70–60/50–10

1/14/14

0.364

Visceral metastases

  

 Present/not present

7/22

0.016*

Number of vertebral metastases

  

 1/2/≥3

9/1/19

0.505

Number of extraspinal metastases

  

 0/1–2/≥3

19/2/8

0.920

Preoperative Frankel score

  

 A–C (not ambulatory)/D–E (ambulatory)

19/10

0.713

Revised Tokuhashi scores

  

 0–8/9–11/12–15

7/16/6

0.048*

Tomita scores

  

 7–10/2–6

6/23

0.084*

Crnalic prostate scores

  

 0–1/2–4/5–6

7/20/2

0.133

PSA

  

 <100/≥100

13/16

0.843

Hormone status 1

  

 Hormone-naïve/hormone-refractory

20/9

0.024*

Hormone status 2

  

 Hormone-naïve 1/hormone-naïve 2/hormone-refractory

16/4/9

0.109

Bisphosphonate treatment

  

 Yes/no

16/13

0.011*

Urinary and bowel continence

  

 Yes/no

24/5

0.900

History of PCa

  

 Yes/no

15/14

0.386

  1. Hormone-naïve 1 means patients with spinal metastases as the initial manifestation of PCa. Hormone-naïve 2 means patients who previously underwent prostatectomy and did not receive hormonal therapy
  2. *P value less than 0.1 for the multivariate analysis