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Table 4 Side effects and incidence of discontinuation of therapy in patients who received adjuvant chemotherapy

From: Effectiveness of adjuvant chemotherapy for elderly patients with lymph node-positive colorectal cancer

   Age <75 years Age >75 years
   Single Combination Single Combination
n 71 44 15 6
Side effects ≥grade 3 13 (18.3 %) 19 (43.1 %) 0 (0 %) 2 (33.3 %)
Signs and symptoms     
 Neutropenia 3 9 0 2
 Anorexia 3 3 0 0
 Diarrhea 3 2 0 0
 Pneumonia 0 1 0 0
 Anaphylaxis 0 1 0 0
 General fatigue 0 1 0 0
 Perforation 0 1 0 0
 Acute leukoencephalopathy 0 1 0 0
 Liver dysfunction 1 0 0 0
 Hand-foot syndrome 1 0 0 0
 Hyperbilirubinemia 2 0 0 0
Discontinuation 8 (11.3 %) 6 (13.6 %) 1 (6.7 %) 0 (0 %)