Table 4 Side effects and incidence of discontinuation of therapy in patients who received adjuvant chemotherapy
| Â | Â | Age <75Â years | Age >75Â years | ||
|---|---|---|---|---|---|
| Â | Â | Single | Combination | Single | Combination |
n | 71 | 44 | 15 | 6 | |
Side effects ≥grade 3 | 13 (18.3 %) | 19 (43.1 %) | 0 (0 %) | 2 (33.3 %) | |
Signs and symptoms | Â | Â | Â | Â | |
 Neutropenia | 3 | 9 | 0 | 2 | |
 Anorexia | 3 | 3 | 0 | 0 | |
 Diarrhea | 3 | 2 | 0 | 0 | |
 Pneumonia | 0 | 1 | 0 | 0 | |
 Anaphylaxis | 0 | 1 | 0 | 0 | |
 General fatigue | 0 | 1 | 0 | 0 | |
 Perforation | 0 | 1 | 0 | 0 | |
 Acute leukoencephalopathy | 0 | 1 | 0 | 0 | |
 Liver dysfunction | 1 | 0 | 0 | 0 | |
 Hand-foot syndrome | 1 | 0 | 0 | 0 | |
 Hyperbilirubinemia | 2 | 0 | 0 | 0 | |
Discontinuation | 8 (11.3Â %) | 6 (13.6Â %) | 1 (6.7Â %) | 0 (0Â %) | |